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Table of Contents
Intro; Preface; Contents; Abbreviations; List of Figures; List of Tables; List of Schemes; Summary of Contents; 1 Classification of Iridoids; 1.1 Introduction; 1.2 The Numbering of Substituted Iridoid and Secoiridoid Glucosides; 1.3 Classification of Iridoids; References; 2 Occurrence and Distribution of Iridoids; 2.1 Introduction; 2.2 Occurrence of Iridoids in Plants; 2.3 Distribution of Iridoids in Plants; 2.4 Iridoid Content in Plant's Organs; 2.5 Iridoids in Insects; 2.6 Iridoid Content in Insect's Organs; References; 3 Isolation and Identification of Iridoids; 3.1 Introduction
3.2 Extraction of Iridoids from Plants and Insects3.3 Isolation Techniques of Iridoids; 3.3.1 Thin-Layer Chromatography; 3.3.2 Open-Column Chromatography; 3.3.3 High-, Medium-, and Low-Performance Liquid Chromatography Techniques; 3.3.4 Droplet- and High-Speed Countercurrent Chromatography Techniques; 3.3.5 Gas-Liquid Chromatography; 3.3.6 Capillary Electrophoresis; 3.4 Spectroscopic Methods for Identification of Iridoids; 3.4.1 UV and IR Spectroscopic Methods; 3.4.2 1H-NMR Spectroscopy; 3.4.3 13C-NMR Spectroscopy; 3.4.3.1 Substituent Effects; 3.4.3.2 Substituent Effect of Hydroxyl Group
3.4.3.3 Substituent Effects on Acetylation and Methylation3.4.3.4 Effects of Keto and Olefinic Groups; 3.4.4 2D-NMR Spectroscopy; 3.4.5 Mass Spectrometry; 3.4.5.1 EI-Mass Spectrometry; 3.4.5.2 ESI-Mass Spectrometry; 3.4.6 X-Ray Crystallographic Study; References; 4 Chemistry and Biosynthesis of Iridoids; 4.1 Introduction; 4.2 Syntheses and Transformations of Bioactive Iridoids; 4.2.1 Syntheses of Bioactive Iridoids; 4.2.2 Transformations of Bioactive Iridoids; 4.3 Syntheses and Transformations of Bioactive Secoiridoids; 4.3.1 Syntheses of Bioactive Secoiridoids
4.3.2 Transformations of Bioactive Secoiridoids4.4 General Biosynthetic Pathway of Plant Iridoids and Secoiridoids; 4.5 Transcriptome and Metabolome Analyses in Iridoid Biosynthesis; 4.6 Biosynthesis of Iridoids in Insects; 4.7 Biosynthesis of Iridoids in Lamiaceae; 4.8 Iridoids as Taxonomic and Phylogenic Markers in Plants; References; 5 Pharmacology of Iridoids; 5.1 Introduction; 5.2 Pharmacology of Iridoids; 5.2.1 Anti-inflammatory and Antinociceptive Activities; 5.2.2 Anti-arthritic Activity; 5.2.3 Hepatoprotective Activity; 5.2.4 Neuroprotective Activity; 5.2.5 Cardioprotective Activity
5.2.6 Anti-allergic Activity5.2.7 Hypoglycemic, Hypolipidemic, and Anti-obesity Activities; 5.2.8 Renoprotective Activity; 5.2.9 Antiglycation Activity; 5.2.10 Pancreas Protective Activity; 5.2.11 Antitumor/Anticancer Activity; 5.2.12 Anticolitis Activity; 5.2.13 Gastroprotective Activity; 5.2.14 Wound-Healing Activity; 5.2.15 Choleretic Activity; 5.2.16 Ocular Hypotensive and Antifibrogenic Activities; 5.2.17 Antioxidant Activity; 5.2.18 Antibacterial and Antifungal Activities; 5.2.19 Antiviral Activity; 5.2.20 Anti-amoebic Activity; 5.2.21 Antimalarial Activity
3.2 Extraction of Iridoids from Plants and Insects3.3 Isolation Techniques of Iridoids; 3.3.1 Thin-Layer Chromatography; 3.3.2 Open-Column Chromatography; 3.3.3 High-, Medium-, and Low-Performance Liquid Chromatography Techniques; 3.3.4 Droplet- and High-Speed Countercurrent Chromatography Techniques; 3.3.5 Gas-Liquid Chromatography; 3.3.6 Capillary Electrophoresis; 3.4 Spectroscopic Methods for Identification of Iridoids; 3.4.1 UV and IR Spectroscopic Methods; 3.4.2 1H-NMR Spectroscopy; 3.4.3 13C-NMR Spectroscopy; 3.4.3.1 Substituent Effects; 3.4.3.2 Substituent Effect of Hydroxyl Group
3.4.3.3 Substituent Effects on Acetylation and Methylation3.4.3.4 Effects of Keto and Olefinic Groups; 3.4.4 2D-NMR Spectroscopy; 3.4.5 Mass Spectrometry; 3.4.5.1 EI-Mass Spectrometry; 3.4.5.2 ESI-Mass Spectrometry; 3.4.6 X-Ray Crystallographic Study; References; 4 Chemistry and Biosynthesis of Iridoids; 4.1 Introduction; 4.2 Syntheses and Transformations of Bioactive Iridoids; 4.2.1 Syntheses of Bioactive Iridoids; 4.2.2 Transformations of Bioactive Iridoids; 4.3 Syntheses and Transformations of Bioactive Secoiridoids; 4.3.1 Syntheses of Bioactive Secoiridoids
4.3.2 Transformations of Bioactive Secoiridoids4.4 General Biosynthetic Pathway of Plant Iridoids and Secoiridoids; 4.5 Transcriptome and Metabolome Analyses in Iridoid Biosynthesis; 4.6 Biosynthesis of Iridoids in Insects; 4.7 Biosynthesis of Iridoids in Lamiaceae; 4.8 Iridoids as Taxonomic and Phylogenic Markers in Plants; References; 5 Pharmacology of Iridoids; 5.1 Introduction; 5.2 Pharmacology of Iridoids; 5.2.1 Anti-inflammatory and Antinociceptive Activities; 5.2.2 Anti-arthritic Activity; 5.2.3 Hepatoprotective Activity; 5.2.4 Neuroprotective Activity; 5.2.5 Cardioprotective Activity
5.2.6 Anti-allergic Activity5.2.7 Hypoglycemic, Hypolipidemic, and Anti-obesity Activities; 5.2.8 Renoprotective Activity; 5.2.9 Antiglycation Activity; 5.2.10 Pancreas Protective Activity; 5.2.11 Antitumor/Anticancer Activity; 5.2.12 Anticolitis Activity; 5.2.13 Gastroprotective Activity; 5.2.14 Wound-Healing Activity; 5.2.15 Choleretic Activity; 5.2.16 Ocular Hypotensive and Antifibrogenic Activities; 5.2.17 Antioxidant Activity; 5.2.18 Antibacterial and Antifungal Activities; 5.2.19 Antiviral Activity; 5.2.20 Anti-amoebic Activity; 5.2.21 Antimalarial Activity