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Intro; Preface; Acknowledgments; Contents; Contributors; 1: Healthy Aging: Definition and Scope; Age; Old Age; Age-Related Changes; Human Demographics; Healthy Aging; Why Healthy Aging Is Important; The Scope of This Book; Summary; References; 2: Disease, Disability, and Frailty with Increasing Age; Changes in the Demographics of Aging; Burden of Diseases and Comorbidities with Aging; Dementia; Obesity; Diabetes; COPD; Cancer; Depression; Cardiovascular Disease; Disability; Clinical Challenges of Multiple Comorbidities; Frailty Definition, Epidemiology, and Consequences

Frailty Definition and PhenotypesEpidemiology of Frailty; Consequences and Burden of Frailty; Conclusion; References; 3: The Principles of Disease and Disability Prevention and Health Promotion with Increasing Age; Introduction; Disease and Disability Prevention; Health Promotion; Shared Decision-Making; References; 4: The Interface Between Healthy Aging, Longevity, Disease, and Disability; Defining Healthy Aging; The Fries Model Versus the Gruenberg Model; The Connection Between Healthy Aging and Longevity; The Connection Between Chronic Disease, Function, Engagement, and Quality of Life

Recent Trends in LongevityRecent Trends in Onset and Progression of Chronic Disease; Recent Trends in Function; Implications for Healthy Aging; Healthy Lifestyle and Its Impact on Healthy Aging; Conclusions; References; 5: Cardiovascular Health and Healthy Aging; Physiologic Changes with Aging; Vascular; Arterial Stiffening; Endothelial Dysfunction; Cardiac; Changes in Cardiac Morphology; Changes in Cardiac Function; Changes in Aerobic Capacity; Cardiovascular Disease: Disability and Frailty; Frailty; Cardiovascular Disease: Risk Factors and Risk Reduction; Sex; Obesity

Risk Reduction Through Voluntary Weight LossCigarette Smoking; Risk Reduction Through Smoking Cessation; Hypertension; Hypertension and Disability; Dyslipidemia; Use of Statin Drugs with Age; Diabetes Mellitus; Metabolic Syndrome; Sedentary Behavior; Subclinical Vascular Abnormalities and Atherosclerosis; Use of Aspirin in Older Adults; Subclinical Vascular Disease and Disability; Cardiac Conditions Common in Older Adults; Atrial Fibrillation; Heart Failure; Heart Failure Disability and Frailty; Aortic Stenosis; Aortic Stenosis, Disability, and Frailty; Peripheral Arterial Disease; Conclusion

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