000866490 000__ 04476cam\a2200457Ii\4500 000866490 001__ 866490 000866490 005__ 20230306145715.0 000866490 006__ m\\\\\o\\d\\\\\\\\ 000866490 007__ cr\cn\nnnunnun 000866490 008__ 190401s2019\\\\si\\\\\\o\\\\\000\0\eng\d 000866490 020__ $$a9789811360046$$q(electronic book) 000866490 020__ $$a9811360049$$q(electronic book) 000866490 020__ $$z9789811360039 000866490 035__ $$aSP(OCoLC)on1091029083 000866490 035__ $$aSP(OCoLC)1091029083 000866490 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dGW5XE$$dEBLCP 000866490 049__ $$aISEA 000866490 050_4 $$aT174.7 000866490 08204 $$a620.5$$223 000866490 24500 $$aNanotechnology in modern animal biotechnology :$$brecent trends and future perspectives /$$cSanjay Singh, Pawan Kumar Maurya, editors. 000866490 264_1 $$aSingapore :$$bSpringer,$$c2019. 000866490 300__ $$a1 online resource 000866490 336__ $$atext$$btxt$$2rdacontent 000866490 337__ $$acomputer$$bc$$2rdamedia 000866490 338__ $$aonline resource$$bcr$$2rdacarrier 000866490 5050_ $$aIntro; Preface; Acknowledgements; Contents; About the Editors; Novel Therapeutics and Diagnostics Strategies Based on Engineered Nanobiomaterials; 1 Introduction; 2 Salient Features of Nanomaterials; 3 Biomedical Applications of Nanomaterials; 3.1 Bone Tissue Engineering; 3.2 Stem Cell Therapy; 3.3 Potential Therapeutics for Neurodegeneration; 3.4 Cancer Therapy; 3.5 Wound Healing Applications; 4 Drug Delivery; 4.1 Nano-emulsions; 4.2 Inorganic Nanoparticles; 4.2.1 Gold Nanoparticles (AuNPs); 4.2.2 Iron Oxide Nanoparticles (IONPs); 4.2.3 Silver Nanoparticles (AgNPs); 4.2.4 Quantum Dots (QDs) 000866490 5058_ $$a5 Nanomaterials in Diagnostics5.1 Nanocomposites; 5.2 Nanoparticles; 5.3 Quantum Dots; 6 Conclusions and Future Prospective; References; Gold Nanostructures for Photothermal Therapy; 1 Introduction; 2 Types of Gold Nanostructures and Their Optical Properties; 2.1 Gold Nanospheres; 2.2 Gold Nanorods; 2.3 Gold Nanoshells; 2.4 Gold Nanocages and Nanorattles; 2.5 Gold Nanostars (GNSTs) and Gold Nanopopcorns (GNPs); 3 Mechanism of Heat Generation and Cell Death Induced by Plasmonic Photothermal Therapy (PTT); 3.1 Mechanism of Heat Generation; 3.2 Mechanism of Cell Death; 3.2.1 Apoptosis 000866490 5058_ $$a3.2.2 Necrosis3.2.3 Secondary or Apoptotic Necrosis; 3.2.4 Factors Affecting Plasmonic Photothermal Therapy (PPTT); 3.2.5 Mechanism of Plasmonic Photothermal Therapy (PPTT); 4 Plasmonic Photothermal Therapy by Different Gold Nanostructures; 4.1 Gold Nanospheres; 4.2 Gold Nanorods (GNRs); 4.3 Gold Nanoshells (GNSs); 4.4 Gold Nanocages (GNCs) and Gold Nanorattles (GNRTs); 4.5 Gold Nanostars (GNSTs) and Gold Nanopopcorns (GNPs); 4.6 Gold Nanoaggregates; 5 Summary and Outlook; References; Nanomaterials-Based siRNA Delivery: Routes of Administration, Hurdles and Role of Nanocarriers 000866490 5058_ $$a1 Introduction1.1 Mechanism of siRNA Interference; 2 Advantages of siRNA; 2.1 Potency; 2.2 Selectivity; 2.3 Safe and Cheap Alternative; 3 Routes of Administration of siRNA; 3.1 Localized Delivery; 3.1.1 Topical Administration; 3.1.2 Ocular Administration; 3.1.3 Pulmonary Administration; 3.1.4 Gastrointestinal Administration; 3.1.5 Central Nervous System Administration; 3.1.6 Vaginal Administration; 3.2 Systemic Delivery; 3.2.1 Oral Administration; 3.2.2 Intravenous Administration; 3.2.3 Intraperitoneal Administration; 4 Major Hurdles to the Therapeutic Delivery of siRNA; 4.1 Transient Effect 000866490 5058_ $$a4.2 Stability4.3 Physiological Barriers; 4.4 Cellular Uptake and Endosomal Engulfing; 4.5 Off-Target Effect; 4.6 Saturation of RNAi Machinery; 4.7 Stimulation of Immune System by siRNAs; 5 Overcoming the Hurdles to siRNA Delivery Using Nanocarriers; 6 The Aid of Nanocarriers for siRNA Delivery; 6.1 Enhanced Blood Retention Time; 6.2 Enhanced Stability and Cell Penetration Property; 6.3 Site-Specific Delivery; 6.4 pH-Sensitive Trigger Release; 6.5 Avoid Intracellular Endosomal Engulfing; 7 Classification of Nanocarriers Used for Systemic Delivery of siRNA; 7.1 Organic Nanocarriers 000866490 506__ $$aAccess limited to authorized users. 000866490 588__ $$aOnline resource; title from PDF title page (viewed April 2, 2019) 000866490 650_0 $$aNanotechnology. 000866490 650_0 $$aBiotechnology. 000866490 650_0 $$aBiotechnology industries. 000866490 7001_ $$aSingh, Sanjay,$$eeditor. 000866490 7001_ $$aMaurya, Pawan Kumar,$$eeditor. 000866490 852__ $$bebk 000866490 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-13-6004-6$$zOnline Access$$91397441.1 000866490 909CO $$ooai:library.usi.edu:866490$$pGLOBAL_SET 000866490 980__ $$aEBOOK 000866490 980__ $$aBIB 000866490 982__ $$aEbook 000866490 983__ $$aOnline 000866490 994__ $$a92$$bISE