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000866628 020__ $$a9780143111313$$q(paperback)
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000866628 05000 $$aRA644.M5$$bW33 2017
000866628 08200 $$a614.5/23$$223
000866628 1001_ $$aWadman, Meredith,$$eauthor.
000866628 24514 $$aThe vaccine race :$$bscience, politics, and the human costs of defeating disease /$$cMeredith Wadman.
000866628 264_1 $$aNew York, New York :$$bViking,$$c[2017]
000866628 300__ $$a436 pages, 16 unnumbered pages of plates :$$billustrations, portraits ;$$c24 cm
000866628 336__ $$atext$$btxt$$2rdacontent
000866628 337__ $$aunmediated$$bn$$2rdamedia
000866628 338__ $$avolume$$bnc$$2rdacarrier
000866628 504__ $$aIncludes bibliographical references (pages 415-419) and index.
000866628 5050_ $$aBeginnings -- Discovery -- The Wistar reborn -- Abnormal chromosomes and abortions -- Dying cells and dogma -- The Swedish source -- Polio vaccine "Passengers" -- Trials -- An emerging enemy -- Plague of the pregnant -- Rabies -- Orphans and ordinary people -- The devils we know -- Politics and persuasion -- The great escape -- In the bear pit -- Cell Wars -- DBS defeated -- Breakthrough -- Slaughtered babies and Skylab -- Cell, Inc. -- Rocky passage -- The vaccine race -- Biology, Inc. -- Hayflick's limit explained -- Boot-camp bugs and Vatican entreaties -- The afterlife of a cell -- Where they are now.
000866628 520__ $$a"The epic and controversial story of a major breakthrough in cell biology that led to the creation of some of the world's most important vaccines. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman's masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who "owns" research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race"--$$cProvided by publisher.
000866628 650_0 $$aRubella vaccines$$xResearch$$zUnited States$$xHistory$$y20th century.
000866628 650_0 $$aRubella vaccines$$xPolitical aspects$$zUnited States$$xHistory$$y20th century.
000866628 650_0 $$aRubella$$xVaccination$$xHistory$$y20th century.
000866628 650_0 $$aMMR vaccine$$xResearch$$zUnited States$$xHistory$$y20th century.
000866628 650_0 $$aHuman experimentation in medicine$$zUnited States$$xHistory$$y20th century.
000866628 650_0 $$aHuman experimentation in medicine$$xPolitical aspects$$zUnited States$$xHistory$$y20th century.
000866628 85200 $$bgen$$hRA644.M5$$iW33$$i2017
000866628 909CO $$ooai:library.usi.edu:866628$$pGLOBAL_SET
000866628 980__ $$aBIB
000866628 980__ $$aBOOK