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Table of Contents
Intro; Preface; Contents; 1: A Brief History of Embryology: Historical Vignettes in Embryology; Suggested Reading; 2: General Embryology; Female Reproductive Tract; Ovary; Genital Ducts; Ovaries (Fig. 2.2); Uterine Tubes; Uterus; Male Reproductive Tract; Testes; Epididymis; Vas (Ductus) Deferens; Accessory Glands; Penis; Gametogenesis; Oogenesis; Formation of the Graafian Follicle; Fate of the Graafian Follicle and the Ovum; Spermatogenesis and Spermiogenesis; Spermiogenesis; Fertilisation; Results of Fertilisation; Implantation; Week 2 of Pregnancy; Trophoblast; Embryonic Layers and Cavities
Amniotic CavityYolk Sac; Week 3; Ectoderm; The Neural Tube; Differentiation of the Neural Tube; Mesoderm (Fig. 2.21); Intermediate Mesoderm; Lateral Plate Mesoderm; Endoderm; 3: Embryology of the Foetal Membranes and Placenta; The Amnion; The Yolk Sac; The Chorion; The Placenta; Abnormalities of the Placenta; Size and Shape Anomalies; Abnormalities of Position; 4: Foetal Circulation; Changes in the Circulation After Birth; General Remarks About the Foetal Circulation; Foetal and Transitional Circulation; References; 5: Teratogenesis and Infection; Overview of Teratogenesis
Principles of TeratologyDrugs; Thalidomide; Nutrients; Folic Acid; Vitamin A; Infections; Cytomegalovirus (CMV); Rubella; Varicella Zoster; Zika Virus; Toxins; Alcohol; Maternal Conditions; Diabetes; Phenylketonuria (PKU); Further Reading; 6: Embryological Basis of Congenital Anomalies; Definition of Congenital Anomalies; Aetiology of Congenital Anomalies; Genetic Defects; Chromosomal Aberrations; Epigenetic Modifications; Environmental Factors; The Concept of Developmental Field; Terminology of Congenital Anomalies; Primary Congenital Defects; Abnormalities of Monozygous Twinning; References
7: Antenatal Screening/Prenatal DiagnosisIntroduction; Aim; Epidemiology of Foetal Anomalies; Routine Testing; First Trimester Screening; Second Trimester Screening; Amniocentesis; Chorion Villus Sampling; Laboratory Analysis; Cytogenetic Analysis; DNA Analysis; Biochemical and Enzymatic Analysis; Diagnosis of Structural Abnormalities; Neural Tube Defects; Congenital Heart Defects; Brief Historical Perspective; Investigations Based on Ultrasound; Three-Dimensional Ultrasound; Foetal MRI; References; 8: Antenatal Counselling and Genetics; Introduction; Case 1; Labour Suite Management
Bowel ReductionRecovery and Feeding; Case 2; References; 9: The Embryological Basis of Behavioural and Psychiatric Conditions; Introduction; The Development of Sense of Self; Development of a Sense of Others; Development of Self-Esteem; Development of Body Image [11]; Is Fear of Difference Normal?; Considering Psychopathology; Myths of Visible Difference (www.changingfaces.org.uk); The Myth of Success; The Myth of Surgery; The Myth of Heroism; The Myth of Horror; The Myth of Learning Difficulties; The Myth that "Appearances Don't Matter"
Amniotic CavityYolk Sac; Week 3; Ectoderm; The Neural Tube; Differentiation of the Neural Tube; Mesoderm (Fig. 2.21); Intermediate Mesoderm; Lateral Plate Mesoderm; Endoderm; 3: Embryology of the Foetal Membranes and Placenta; The Amnion; The Yolk Sac; The Chorion; The Placenta; Abnormalities of the Placenta; Size and Shape Anomalies; Abnormalities of Position; 4: Foetal Circulation; Changes in the Circulation After Birth; General Remarks About the Foetal Circulation; Foetal and Transitional Circulation; References; 5: Teratogenesis and Infection; Overview of Teratogenesis
Principles of TeratologyDrugs; Thalidomide; Nutrients; Folic Acid; Vitamin A; Infections; Cytomegalovirus (CMV); Rubella; Varicella Zoster; Zika Virus; Toxins; Alcohol; Maternal Conditions; Diabetes; Phenylketonuria (PKU); Further Reading; 6: Embryological Basis of Congenital Anomalies; Definition of Congenital Anomalies; Aetiology of Congenital Anomalies; Genetic Defects; Chromosomal Aberrations; Epigenetic Modifications; Environmental Factors; The Concept of Developmental Field; Terminology of Congenital Anomalies; Primary Congenital Defects; Abnormalities of Monozygous Twinning; References
7: Antenatal Screening/Prenatal DiagnosisIntroduction; Aim; Epidemiology of Foetal Anomalies; Routine Testing; First Trimester Screening; Second Trimester Screening; Amniocentesis; Chorion Villus Sampling; Laboratory Analysis; Cytogenetic Analysis; DNA Analysis; Biochemical and Enzymatic Analysis; Diagnosis of Structural Abnormalities; Neural Tube Defects; Congenital Heart Defects; Brief Historical Perspective; Investigations Based on Ultrasound; Three-Dimensional Ultrasound; Foetal MRI; References; 8: Antenatal Counselling and Genetics; Introduction; Case 1; Labour Suite Management
Bowel ReductionRecovery and Feeding; Case 2; References; 9: The Embryological Basis of Behavioural and Psychiatric Conditions; Introduction; The Development of Sense of Self; Development of a Sense of Others; Development of Self-Esteem; Development of Body Image [11]; Is Fear of Difference Normal?; Considering Psychopathology; Myths of Visible Difference (www.changingfaces.org.uk); The Myth of Success; The Myth of Surgery; The Myth of Heroism; The Myth of Horror; The Myth of Learning Difficulties; The Myth that "Appearances Don't Matter"