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Intro; Preface to the Second Edition; Preface to the First Edition; Preface to the First eBook Edition; Contents; 1: Diagnostic Clues for Thyroid Aspiration Cytology; 1.1 Introduction; 1.2 Background; 1.2.1 Colloid; 1.2.2 Watery Colloid; 1.2.3 Dense Colloid; 1.2.4 Ropy Colloid; 1.2.5 Amyloid; 1.2.6 Inflammatory Cells; 1.2.7 Psammoma Bodies; 1.2.8 Lymphoglandular Bodies; 1.2.9 Necrotic Materials; 1.3 Arrangements; 1.3.1 Microfollicles; 1.3.2 Papillary Tissue Fragment; 1.3.3 Crinkled (Bended) Monolayered Sheets; 1.3.4 Cap; 1.3.5 Cellular Swirl; 1.3.6 Hobnail Pattern
1.3.7 Ball-Like Clusters1.4 Cell Shapes; 1.4.1 Tall Cells; 1.4.2 Spindle Cells; 1.4.3 Tail-like Cytoplasmic Elongation; 1.5 Cytoplasm; 1.5.1 Oxyphilic Cells; 1.5.2 Septate Intracytoplasmic Vacuoles; 1.5.3 Intracytoplasmic Lumina; 1.5.4 Yellow Bodies; 1.5.5 Paravacuolar Granules; 1.5.6 Metachromatic Granules; 1.5.7 Emperipolesis; 1.6 Nuclei; 1.6.1 Ground Glass Nuclei; 1.6.2 Intranuclear Cytoplasmic Inclusions; 1.6.3 Nuclear Grooves; 1.6.4 Nuclear Overlapping; 1.6.5 Polylobulated Nuclei; 1.6.6 Binucleated Cells; 1.6.7 Convoluted Nuclei; 1.6.8 Peculiar Nuclear Clearing
1.6.9 Salt and Pepper ChromatinReferences; 2: Factors Impacting Thyroid Fine Needle Aspiration Cytology and Algorithm for Cytological Diagnosis in the Japanese System for Reporting FNA Cytology; 2.1 Diagnostic Systems for Thyroid FNA Cytology; 2.1.1 History of Diagnostic Systems in Different Countries; 2.1.2 The Japanese System for Reporting Thyroid FNA Cytology
2.1.3 Subclassification of the FN/SFN Category in the Japanese System Is Key in Risk Stratification of FN/SFN Nodules and Establishes Low Resection Rates and High Risks of Malignancy on Histology, Which Ultimately Reduces Overtreatment of Borderline2.1.4 Why Is Diagnostic Surgery Recommended to Patients with FN/SFN Nodules in Western Practice?; 2.2 Diagnostic Algorithm in the Japanese System (Fig. 2.1); 2.3 Other Factors Discussed in the First Edition of Thyroid FNA Cytology, Differential Diagnoses, and Pitfalls
2.4 Proposal of New Diagnostic Categories for Reporting Thyroid FNA Cytology2.5 Histological Type-Oriented Classification Is Key for Selecting Molecular Tests for a More Definitive Diagnosis; 2.6 Morphological Criteria and Observer Disagreement; 2.7 Cyst Fluid-Only Sample as an Example to Explain Different Clinical Approaches Among Practices; References; 3: False Positive in Thyroid FNA: Causes and How to Avoid Them; 3.1 Introduction; 3.2 Cystic Lesions; 3.3 Inflammatory Lesions; 3.3.1 Acute Suppurative Thyroiditis; 3.3.2 Granulomatous Thyroiditis; 3.3.3 Lymphocytic Thyroiditis; 3.4 Follicular-Pattern Lesions
1.3.7 Ball-Like Clusters1.4 Cell Shapes; 1.4.1 Tall Cells; 1.4.2 Spindle Cells; 1.4.3 Tail-like Cytoplasmic Elongation; 1.5 Cytoplasm; 1.5.1 Oxyphilic Cells; 1.5.2 Septate Intracytoplasmic Vacuoles; 1.5.3 Intracytoplasmic Lumina; 1.5.4 Yellow Bodies; 1.5.5 Paravacuolar Granules; 1.5.6 Metachromatic Granules; 1.5.7 Emperipolesis; 1.6 Nuclei; 1.6.1 Ground Glass Nuclei; 1.6.2 Intranuclear Cytoplasmic Inclusions; 1.6.3 Nuclear Grooves; 1.6.4 Nuclear Overlapping; 1.6.5 Polylobulated Nuclei; 1.6.6 Binucleated Cells; 1.6.7 Convoluted Nuclei; 1.6.8 Peculiar Nuclear Clearing
1.6.9 Salt and Pepper ChromatinReferences; 2: Factors Impacting Thyroid Fine Needle Aspiration Cytology and Algorithm for Cytological Diagnosis in the Japanese System for Reporting FNA Cytology; 2.1 Diagnostic Systems for Thyroid FNA Cytology; 2.1.1 History of Diagnostic Systems in Different Countries; 2.1.2 The Japanese System for Reporting Thyroid FNA Cytology
2.1.3 Subclassification of the FN/SFN Category in the Japanese System Is Key in Risk Stratification of FN/SFN Nodules and Establishes Low Resection Rates and High Risks of Malignancy on Histology, Which Ultimately Reduces Overtreatment of Borderline2.1.4 Why Is Diagnostic Surgery Recommended to Patients with FN/SFN Nodules in Western Practice?; 2.2 Diagnostic Algorithm in the Japanese System (Fig. 2.1); 2.3 Other Factors Discussed in the First Edition of Thyroid FNA Cytology, Differential Diagnoses, and Pitfalls
2.4 Proposal of New Diagnostic Categories for Reporting Thyroid FNA Cytology2.5 Histological Type-Oriented Classification Is Key for Selecting Molecular Tests for a More Definitive Diagnosis; 2.6 Morphological Criteria and Observer Disagreement; 2.7 Cyst Fluid-Only Sample as an Example to Explain Different Clinical Approaches Among Practices; References; 3: False Positive in Thyroid FNA: Causes and How to Avoid Them; 3.1 Introduction; 3.2 Cystic Lesions; 3.3 Inflammatory Lesions; 3.3.1 Acute Suppurative Thyroiditis; 3.3.2 Granulomatous Thyroiditis; 3.3.3 Lymphocytic Thyroiditis; 3.4 Follicular-Pattern Lesions