Landmark trials in oncology / Santosh Yajnik.
Yajnik, Santosh, author.
2019
R853.C55
Available Online

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Title Landmark trials in oncology / Santosh Yajnik.
Author Yajnik, Santosh, author.
ISBN 9783030144050 (electronic book)
3030144054 (electronic book)
9783030144043
DOI https://doi.org/10.1007/978-3-030-14405-0
Published Cham : Springer, 2019.
Language English
Description 1 online resource (ix, 325 pages) : illustrations
Item Number 10.1007/978-3-030-14405-0 doi
Call Number R853.C55
Dewey Decimal Classification 616.99/4027
Summary This book describes the evolution of treatment in oncology through the lens of approximately 250 landmark clinical trials. The well-designed clinical trial is essential to the practice of medicine. There is no field that has embraced or been transformed more by the clinical trial than oncology. Each primary cancer site has a remarkable story that can be told through clinical trials. For example, patients who presented decades ago with soft tissue sarcoma of the extremities would invariably undergo limb amputation. The landmark National Cancer Institute study by Rosenberg et al. randomized patients to limb sparing surgery followed by adjuvant radiation therapy compared with limb amputation. This study helped change the standard of care by allowing most patients to retain their functioning limbs with an improvement in quality of life and no compromise in overall survival. Such major clinical trials for common malignancies including breast, prostate, lung, gastrointestinal, genitourinary, and gynecologic cancers are discussed. Because oncology is multidisciplinary, this book should be of interest for radiation oncologists, surgeons, medical oncologists, and other physicians interested in learning more about the landmark trials that have shaped oncology.
Access Note Access limited to authorized users.
Digital File Characteristics text file PDF
Source of Description Online resource; title from PDF title page (SpringerLink, viewed May 14, 2019).
Available in Other Form Print version: 9783030144043
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Intro; Preface; Contents; 1: Introduction to Landmark Trials in Oncology; Bibliography; 2: Landmark Trials in Breast Cancer; 2.1 Introduction; 2.2 Breast Cancer; 2.3 Selected Pending and Future Landmark Trials; Bibliography; 3: Landmark Trials in Lung Cancer; 3.1 Introduction; 3.1.1 Non-small Cell Lung Cancer; 3.1.2 Small Cell Lung Cancer; 3.1.3 Summary; 3.2 Non-small Cell Lung Cancer; 3.3 Small Cell Lung Cancer; 3.4 Selected Pending and Future Landmark Trials; 3.4.1 Non-small Cell Lung Cancer; 3.4.2 Small Cell Lung Cancer; Bibliography; Non-small Cell Lung Cancer

Small Cell Lung Cancer4: Landmark Trials in Selected Genitourinary Malignancies; 4.1 Introduction; 4.1.1 Prostate Cancer; 4.1.2 Bladder Cancer; 4.1.3 Renal Cancer; 4.1.4 Testicular Cancer; 4.1.5 Summary; 4.2 Prostate Cancer; 4.3 Bladder Cancer; 4.4 Renal Cancer; 4.5 Testicular Cancers; 4.6 Selected Pending and Future Landmark Trials; 4.6.1 Prostate Cancer; 4.6.2 Bladder Cancer; 4.6.3 Renal Cancer; Bibliography; Prostate Cancer; Bladder Cancer; Renal Cancer; Testicular Seminoma; 5: Landmark Trials in Selected Gastrointestinal Cancers; 5.1 Introduction; 5.1.1 Esophageal Cancer

5.1.2 Gastric Cancer5.1.3 Pancreatic Cancer; 5.1.4 Colon Cancer; 5.1.5 Rectal Cancer; 5.1.6 Anal Cancer; 5.1.7 Summary; 5.2 Esophageal Cancer; 5.3 Gastric Cancer; 5.4 Pancreas Cancer; 5.5 Colon Cancer; 5.6 Rectal Cancer; 5.7 Anal Cancer; 5.8 Selected Pending and Future Landmark Trials; 5.8.1 Esophageal Cancer; 5.8.2 Gastric Cancer; 5.8.3 Pancreas Cancer; 5.8.4 Colon Cancer; 5.8.5 Rectal Cancer; 5.8.6 Anal Cancer; Bibliography; Esophageal Cancer; Gastric Cancer; Pancreas Cancer; Colon Cancer; Rectal Cancer; Anal Cancer; 6: Landmark Trials in Selected Gynecologic Cancers

6.1 Introduction6.1.1 Endometrial Cancer; 6.1.2 Cervical Cancer; 6.1.3 Ovarian Cancer; 6.1.4 Vulvar Cancer; 6.1.5 Summary; 6.2 Endometrial Cancer; 6.3 Cervical Cancer; 6.4 Ovarian Cancer; 6.5 Vulvar Cancer; 6.6 Selected Pending and Future Landmark Trials; 6.6.1 Endometrial Cancer; 6.6.2 Cervical Cancer; 6.6.3 Ovarian Cancer; 6.6.4 Vulvar Cancer; Bibliography; Endometrial Cancer; Cervical Cancer; Ovarian Cancer; Vulvar Cancer; 7: Landmark Trials in Selected Head and Neck Cancers; 7.1 Introduction; 7.2 Head and Neck Cancer; 7.3 Selected Pending and Future Landmark Trials

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