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Intro; Dedication; Preface; Acknowledgments; Contents; About the Editors and Contributors; Editors; Contributors; 1: Recent Progress in Research on the Pharmacological Potential of Mushrooms and Prospects for Their Clinical Application; 1.1 Introduction; 1.2 Biological and Genetic Resources of Medicinal Mushrooms and Their Application; 1.3 Mushroom-Derived Bioactive Compounds; 1.3.1 Polysaccharides; 1.3.2 Terpenoids, Steroids, and Sterols; 1.3.3 Phenolics and Other Compounds; 1.4 Pharmacological Activity of Mushrooms; 1.4.1 Antimicrobial (Antifungal and Antibacterial) Activity
1.4.2 Immunomodulatory and Anticancer Activities1.4.3 Hypocholesterolemic, Hypoglycemic, and Anti-obesity Effects; 1.4.4 Antioxidant and Anti-inflammatory Effects; 1.4.5 Cardioprotective Effect; 1.4.6 Neuroprotective and Antidepressant Effects; 1.4.7 Antiviral and Anti-allergic Effects; 1.5 Nutritional and Dietary Values of Medicinal Mushrooms; 1.6 Current State of Epidemiological and Clinical Studies of Medicinal Mushrooms; 1.7 Conclusions and Future Prospects; References; 2: Edible Mushrooms as Neuro-nutraceuticals: Basis of Therapeutics; 2.1 Introduction
2.1.1 The Good and Bad Mushrooms2.1.1.1 Edible Mushrooms; 2.1.1.2 Medicinal Mushrooms; 2.1.1.3 Edible Mushrooms with Toxic Effects; 2.1.1.4 Poisonous Mushrooms; 2.2 Mushrooms and Neural Cells; 2.2.1 Neuroprotective Effects of Mushrooms; 2.2.2 Neuro-regenerative Effects of Mushrooms; 2.2.3 Neuronal Differentiation, Stem Cell Generation, and Myelinogenesis; 2.3 Mushrooms and Some Neurological Diseases; 2.3.1 Fatigue and Depression; 2.3.2 Beneficial Effects of Mushrooms in Alzheimer's Disease; 2.3.3 Mushrooms Are Good for Parkinson's Disease
2.4 Mechanisms by Which Mushrooms Exert Medicinal Effects2.4.1 Short-Term or Long-Term ER Stress Have Varied Effects on Neural Health; 2.4.2 Erinacine A Regulates Cellular Oxidant Stress and Immunity to Affect Neuronal Rescue; 2.4.3 Pleurotus giganteus Blocks Nitrosative Stress to Aid in Neuronal Protection; 2.4.4 Amanita caesarea Regulates Ca2+-Mediated Apoptosis and Increases Autophagy in Cells; 2.4.5 Polyozellin Tames Apoptosis During Excitotoxicity; 2.5 Mushrooms as Probiotic: The Gut-Brain Axis; 2.6 Conclusions; References; 3: Overview of Therapeutic Efficacy of Mushrooms
3.1 Introduction3.2 Overview of the Therapeutic Efficacy of Mushrooms; 3.2.1 Beneficial Role of Mushrooms or Mushroom-Derived Substances in Neurological Diseases; 3.2.2 Beneficial Role of Mushrooms or Mushroom-Derived Substances in Cardiovascular Diseases; 3.2.3 Beneficial Role of Mushrooms or Mushroom-Derived Substances in Cancer; 3.2.4 Beneficial Role of Mushrooms or Mushroom-Derived Substances in Diabetes Mellitus; 3.2.5 Beneficial Role of Mushrooms or Mushroom-Derived Substances Against Infectious Diseases
3.2.6 Cytoprotective (Antioxidant, Immunostimulating, and Anti-inflammatory) Properties of Mushrooms
1.4.2 Immunomodulatory and Anticancer Activities1.4.3 Hypocholesterolemic, Hypoglycemic, and Anti-obesity Effects; 1.4.4 Antioxidant and Anti-inflammatory Effects; 1.4.5 Cardioprotective Effect; 1.4.6 Neuroprotective and Antidepressant Effects; 1.4.7 Antiviral and Anti-allergic Effects; 1.5 Nutritional and Dietary Values of Medicinal Mushrooms; 1.6 Current State of Epidemiological and Clinical Studies of Medicinal Mushrooms; 1.7 Conclusions and Future Prospects; References; 2: Edible Mushrooms as Neuro-nutraceuticals: Basis of Therapeutics; 2.1 Introduction
2.1.1 The Good and Bad Mushrooms2.1.1.1 Edible Mushrooms; 2.1.1.2 Medicinal Mushrooms; 2.1.1.3 Edible Mushrooms with Toxic Effects; 2.1.1.4 Poisonous Mushrooms; 2.2 Mushrooms and Neural Cells; 2.2.1 Neuroprotective Effects of Mushrooms; 2.2.2 Neuro-regenerative Effects of Mushrooms; 2.2.3 Neuronal Differentiation, Stem Cell Generation, and Myelinogenesis; 2.3 Mushrooms and Some Neurological Diseases; 2.3.1 Fatigue and Depression; 2.3.2 Beneficial Effects of Mushrooms in Alzheimer's Disease; 2.3.3 Mushrooms Are Good for Parkinson's Disease
2.4 Mechanisms by Which Mushrooms Exert Medicinal Effects2.4.1 Short-Term or Long-Term ER Stress Have Varied Effects on Neural Health; 2.4.2 Erinacine A Regulates Cellular Oxidant Stress and Immunity to Affect Neuronal Rescue; 2.4.3 Pleurotus giganteus Blocks Nitrosative Stress to Aid in Neuronal Protection; 2.4.4 Amanita caesarea Regulates Ca2+-Mediated Apoptosis and Increases Autophagy in Cells; 2.4.5 Polyozellin Tames Apoptosis During Excitotoxicity; 2.5 Mushrooms as Probiotic: The Gut-Brain Axis; 2.6 Conclusions; References; 3: Overview of Therapeutic Efficacy of Mushrooms
3.1 Introduction3.2 Overview of the Therapeutic Efficacy of Mushrooms; 3.2.1 Beneficial Role of Mushrooms or Mushroom-Derived Substances in Neurological Diseases; 3.2.2 Beneficial Role of Mushrooms or Mushroom-Derived Substances in Cardiovascular Diseases; 3.2.3 Beneficial Role of Mushrooms or Mushroom-Derived Substances in Cancer; 3.2.4 Beneficial Role of Mushrooms or Mushroom-Derived Substances in Diabetes Mellitus; 3.2.5 Beneficial Role of Mushrooms or Mushroom-Derived Substances Against Infectious Diseases
3.2.6 Cytoprotective (Antioxidant, Immunostimulating, and Anti-inflammatory) Properties of Mushrooms