000890813 000__ 04531cam\a2200529Ki\4500 000890813 001__ 890813 000890813 005__ 20230306150123.0 000890813 006__ m\\\\\o\\d\\\\\\\\ 000890813 007__ cr\cn\nnnunnun 000890813 008__ 190606s2019\\\\sz\\\\\\o\\\\\001\0\eng\d 000890813 019__ $$a1104474938$$a1105173208 000890813 020__ $$a9783030113551$$q(electronic book) 000890813 020__ $$a3030113558$$q(electronic book) 000890813 020__ $$z303011354X 000890813 020__ $$z9783030113544 000890813 0247_ $$a10.1007/978-3-030-11$$2doi 000890813 035__ $$aSP(OCoLC)on1103464292 000890813 035__ $$aSP(OCoLC)1103464292$$z(OCoLC)1104474938$$z(OCoLC)1105173208 000890813 040__ $$aYDX$$beng$$erda$$cYDX$$dYDXIT$$dLQU$$dGW5XE 000890813 049__ $$aISEA 000890813 050_4 $$aQP572.S4$$bF76 2019 000890813 08204 $$a612.6$$223 000890813 24500 $$aFrontiers in gynecological endocrinology.$$nVolume 6,$$pSex steroids' effects on brain, heart and vessels /$$cRoberta Diaz Brinton, Andrea R. Genazzani, Tommaso Simoncini, John C. Stevenson, editors. 000890813 2463_ $$aSex steroids' effects on brain, heart and vessels 000890813 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2019] 000890813 300__ $$a1 online resource. 000890813 336__ $$atext$$btxt$$2rdacontent 000890813 337__ $$acomputer$$bc$$2rdamedia 000890813 338__ $$aonline resource$$bcr$$2rdacarrier 000890813 4901_ $$aISGE series 000890813 500__ $$aIncludes index. 000890813 5050_ $$a1. Neuroendocrine changes of the menopausal transition -- 2. The neurological and immunological transitions of the perimenopause: implications for post-menopausal neurodegenerative disease -- 3. Estrogenic regulation of neuroprotective and neuroinflammatory mechanisms: implications for depression and cognition -- 4."Estetrol and its effects on damaged brain Running title: Estetrol and brain. 5. ADRENAL ANDROGENS IMPACT ON NEUROSTEROIDS -- 6. Do menopausal symptoms account for the declines in cognitive function during the menopausal transition? -- 7. Allopregnanolone as a therapeutic to regenerate the degenerated brain -- 8. Reproductive Depression and the response to Hormone Therapy -- 9. Sex, Gender, and the Decline of Dementia -- 10. Obstetric History and cardiovascular disease (CVD) Risk -- 11.HRT and Cardiovascular disease -- 12. Estetrol, a Native Estrogen with Specific Actions in Tissues (NEST): Unique vascular benefits -- 13. VASCULAR EFFECTS OF PROGESTOGENS -- 14. Sex differences, progesterone and ischemic stroke -- 16. Atherogenesis -- Estrogen Induction of polysialylated nCAM (PSA-nCAM) Blocks Monocyte Capture by Vascular Endothelial Cells -- 17. Cardiovascular risk in climacteric women: when to begin the hormone treatment? -- 18. HRT for the primary prevention of coronary heart disease -- SYMPTOMS AND HORMONES: FINE-TUNING ATHEROSCLEROTIC RISK ? -- 19. Cardiovascular mortality risk and HRT" -- 20. HT: Pharmacology tailored to women´s health". 000890813 506__ $$aAccess limited to authorized users. 000890813 520__ $$aThis book analyzes the effects of estrogens and progesterone on brain cells, the immune system, neuro inflammation, myelin formation and steroid receptor distribution, as well as their clinical impacts. It also explores the relationship between sex-steroid withdrawal and the development of brain symptoms such as hot flushes, sleep disorders, mood changes, depression and also cognitive disorders and dementia, as well as the effects of hormone menopause therapy on such symptoms and diseases. Starting with obstetrical history and cardiovascular risk in later life, the second part of the book examines the effects of estrogens and progestogens on vascular tissues, atherosclerosis and coronary heart diseases, as well as the impact of hormone replacement therapies on cardiovascular risks and mortality. This volume is a useful, clear and up-to-date tool for gynecologists, endocrinologists, neurologists and cardiologists, and serves as a valuable source of information for all physicians involved in womens health. 000890813 588__ $$aDescription based on online resource; title from digital title page (viewed on June 13, 2019). 000890813 650_0 $$aHormones, Sex$$xPhysiological effect. 000890813 650_0 $$aSteroid hormones$$xPhysiological effect. 000890813 7001_ $$aBrinton, Roberta Diaz,$$eeditor. 000890813 7001_ $$aGenazzani, Andrea R.,$$eeditor. 000890813 7001_ $$aSimoncini, Tommaso,$$eeditor. 000890813 7001_ $$aStevenson, John C.$$q(John Curtis),$$eeditor. 000890813 77608 $$iPrint version $$z303011354X$$z9783030113544$$w(OCoLC)1078762065 000890813 830_0 $$aISGE series. 000890813 852__ $$bebk 000890813 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-11355-1$$zOnline Access$$91397441.1 000890813 909CO $$ooai:library.usi.edu:890813$$pGLOBAL_SET 000890813 980__ $$aEBOOK 000890813 980__ $$aBIB 000890813 982__ $$aEbook 000890813 983__ $$aOnline 000890813 994__ $$a92$$bISE