000891435 000__ 04469cam\a2200469Ii\4500 000891435 001__ 891435 000891435 005__ 20230306150047.0 000891435 006__ m\\\\\o\\d\\\\\\\\ 000891435 007__ cr\cn\nnnunnun 000891435 008__ 190615s2019\\\\si\\\\\\ob\\\\001\0\eng\d 000891435 019__ $$a1106168629 000891435 020__ $$a9789811358951$$q(electronic book) 000891435 020__ $$a9811358958$$q(electronic book) 000891435 020__ $$z9789811358944 000891435 0248_ $$a10.1007/978-981-13-5 000891435 035__ $$aSP(OCoLC)on1104715805 000891435 035__ $$aSP(OCoLC)1104715805$$z(OCoLC)1106168629 000891435 040__ $$aEBLCP$$beng$$erda$$cEBLCP$$dLQU$$dGW5XE$$dEBLCP$$dYDXIT$$dUKMGB 000891435 049__ $$aISEA 000891435 050_4 $$aQP321$$b.S66 2019 000891435 08204 $$a612.7/4045$$223 000891435 24500 $$aSmooth muscle spontaneous activity :$$bphysiological and pathological modulation /$$cHikaru Hashitani, Richard J. Lang, editors. 000891435 264_1 $$aSingapore :$$bSpringer,$$c[2019] 000891435 300__ $$a1 online resource 000891435 336__ $$atext$$btxt$$2rdacontent 000891435 337__ $$acomputer$$bc$$2rdamedia 000891435 338__ $$aonline resource$$bcr$$2rdacarrier 000891435 4901_ $$aAdvances in experimental medicine and biology ;$$vvolume 1124 000891435 504__ $$aIncludes bibliographical references and index. 000891435 5050_ $$aPART I: Gastrointestinal tract -- Phasic muscle -- Spontaneous electrical activity and rhythmicity in gastrointestinal smooth muscles -- Tonic muscle (Sphincters) -- Generation of tone by gastrointestinal sphincters -- PART II: Urinary tract -- Renal pelvis -- Pacemaker mechanisms driving pyeloureteric peristalsis: modulatory role of interstitial cells -- Ureter -- Excitation-contraction coupling in ureteric smooth muscle: mechanisms driving ureteric peristalsis -- Urinary Bladder -- Spontaneous activity and the urinary bladder -- Urethra -- Spontaneous activity in urethral smooth muscle -- PART III: Reproductive organs -- Corporal tissue -- Ion channels and intracellular calcium signalling in corpus cavernosum -- Prostate -- Generation and regulation of spontaneous contractions in the prostate gland -- Seminal vesicle -- Mucosa-dependent, stretch-sensitive spontaneous activity in seminal vesicle -- Uterus -- The myometrium - from excitation to contractions and labour -- Oviducts -- Myosalpinx contractions are essential for egg transport along the oviduct and are disrupted in reproductive tract diseases -- PART IV: Blood vessels -- Artery -- Cellular and Ionic Mechanisms of Arterial Vasomotion -- Vein -- Venous Vasomotion -- Microvasculature -- Role of pericytes in the initiation and propagation of spontaneous activity in the microvasculature -- Lymphatic vessels -- Lymphatic vessel pumping -- PART V: Airways -- Regulation of airway smooth muscle contraction in health and disease. 000891435 506__ $$aAccess limited to authorized users. 000891435 520__ $$aThis book presents the commonality and heterogeneity of the mechanisms underlying smooth muscle spontaneous activity in various smooth muscle organs and in addition discusses their malfunctions in disease and their potential as novel therapeutic targets. To facilitate understanding, the volume is divided into five parts and covers 16 organs: airways, phasic muscle, tonic muscle, renal pelvis, ureter, urinary bladder, urethra, corporal tissue, prostate, uterus, oviducts, seminal vesicle, artery, vein, microvasculature, and lymphatic vessels. This structure will help readers to comprehend the most up-to-date information on the similarities and differences in the contractile mechanisms driving various smooth muscles as well as their potential manipulations in particular visceral organ pathologies. The vast advancements in gene, electrical recording, and imaging technologies in this field are also discussed, with review of past achievements and consideration of likely future developments. This book will be of worldwide interest to clinicians, students, and researchers alike. 000891435 588__ $$aDescription based on online resource; title from digital title page (viewed on July 16, 2019). 000891435 650_0 $$aSmooth muscle. 000891435 7001_ $$aHashitani, Hikaru,$$eeditor. 000891435 7001_ $$aLang, Richard J.,$$eeditor. 000891435 77608 $$iPrint version:$$aHashitani, Hikaru$$tSmooth Muscle Spontaneous Activity : Physiological and Pathological Modulation$$dSingapore : Springer,c2019$$z9789811358944 000891435 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1124. 000891435 852__ $$bebk 000891435 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-13-5895-1$$zOnline Access$$91397441.1 000891435 909CO $$ooai:library.usi.edu:891435$$pGLOBAL_SET 000891435 980__ $$aEBOOK 000891435 980__ $$aBIB 000891435 982__ $$aEbook 000891435 983__ $$aOnline 000891435 994__ $$a92$$bISE