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Zebrafish : a model for marine peptide based drug screening / Saravanan Ramachandran and Senthilkumar Rajago.

Ramachandran, Saravanan, author.; Rajagopal, Senthilkumar, author.
2019
QP552.P4
Available Online
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Title
Zebrafish : a model for marine peptide based drug screening / Saravanan Ramachandran and Senthilkumar Rajago.
Author
Ramachandran, Saravanan, author.
ISBN
9789811378447 (electronic book)
9811378444 (electronic book)
9789811378430
DOI
https://doi.org/10.1007/978-981-13-7
Published
Singapore : Springer, [2019]
Copyright
©2019
Language
English
Description
1 online resource.
Item Number
10.1007/978-981-13-7
Call Number
QP552.P4
Dewey Decimal Classification
572.65
Summary
This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (viewed June 14, 2019).
Added Author
Rajagopal, Senthilkumar, author.
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Chapter 1. Biomedical importance of marine peptides/toxins
Chapter 2. Toxicity of peptides in Zebrafish embryos
Chapter 3. Teratogenic activity of toxins in Zebrafish model
Chapter 4. Anticancer properties marine peptides/toxins using Zebrafish model
Chapter 5. Protective effect of marine peptides/toxins in CVD using Zebrafish model.

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