CPP, cell-penetrating peptides / Ülo Langel.
Langel, Ülo, author.
2019
QD431 .L36 2019
Available Online

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Title CPP, cell-penetrating peptides / Ülo Langel.
Author Langel, Ülo, author.
ISBN 9789811387470 (electronic book)
9811387478 (electronic book)
9789811387463
981138746X
DOI https://doi.org/10.1007/978-981-13-8747-0
Published Singapore : Springer, [2019]
Language English
Description 1 online resource
Other Standard Identifiers 10.1007/978-981-13-8747-0 doi
Call Number QD431 .L36 2019
Dewey Decimal Classification 572/.65
Summary In this book, a summary and update of the most important areas of CPP research are presented, whilst raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. The monograph is written for researchers and students in the field.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Digital File Characteristics text file PDF
Source of Description Description based on online resource; title from digital title page (viewed on July 18, 2019).
Available in Other Form Print version: 9789811387463
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Classes and applications of CPP
CPP functionalization
Protein delivery and mimicry
Targeting strategies
Methods for detection and visualization of CPPs
Methods for structural studies of CPPs
Kinetics
Toxicity and immune response
Cell-translocation mechanisms of CPPs
Clinical trials and commercialization using CPPs
Therapeutic potential of CPPs.

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