ALERT - Adverse Late Effects of Cancer Treatment. Volume 1, General concepts and specific precepts / Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors.

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ALERT - Adverse Late Effects of Cancer Treatment. Volume 1, General concepts and specific precepts / Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors.

9783540723134
3540723137
130620027X (electronic book)
9781306200271 (electronic book)
9783540723141
3540723145
9783540723141

Berlin : Springer Berlin Heidelberg, 2014.

English

1 online resource

10.1007/978-3-540-72314-1 doi

RC270.8

616.99/406
615.842

The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT - Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.

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Medical radiology (Series)

Print version: 9781306200271

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