@article{898782,
      recid = {898782},
      author = {Salgia, Ravi.},
      title = {Targeted Therapies for Lung Cancer /},
      publisher = {Springer,},
      address = {Cham :},
      pages = {1 online resource (244 pages)},
      year = {2019},
      abstract = {This book contextualizes translational research and  provides an up to date progress report on therapies that  are currently being targeted in lung cancer. It is now well  established that there is tremendous heterogeneity among  cancer cells both at the inter- and intra-tumoral level.  Further, a growing body of work highlights the importance  of targeted therapies and personalized medicine in treating  cancer patients. In contrast to conventional therapies that  are typically administered to the average patient  regardless of the patients genotype, targeted therapies are  tailored to patients with specific traits. Nonetheless,  such genetic changes can be disease-specific and/or target  specific; thus, the book addresses these issues manifested  in the somatically acquired genetic changes of the targeted  gene. Each chapter is written by a leading medical  oncologist who specializes in thoracic oncology and is  devoted to a particular target in a specific indication.  Contributors provide an in-depth review of the literature  covering the mechanisms underlying signaling, potential  cross talk between the target and downstream signaling, and  potential emergence of drug resistance.},
      url = {http://library.usi.edu/record/898782},
}