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Table of Contents
Intro; Preface to the Second Edition; Acknowledgment; Contents; Contributors; List of Figures; List of Tables; Part I: Components of Myocardial Performance; 1: Preload; Understanding the Concept; Preload Physiology and Theory; Chamber Anatomy and Function; The Right Atrial Pressure Waveform; Assessing Preload from the Right Atrial Pressure; Preload Reserve and the Venous System; Preload and the Respiratory Cycle; The Pulmonary Capillary Wedge Pressure Waveform; Assessing Preload from the Pulmonary Capillary Wedge Pressure; Preload Dependency and Pressure-Volume Loops
Preload in Clinical PracticeInvasive Hemodynamics; Noninvasive Preload Assessment Techniques; Additional Invasive Preload Assessment Techniques; References; Suggested Reading; 2: Afterload; Understanding the Concept; Afterload Physiology and Theory; Afterload and Arterial Vasculature; Reflected Pressure Waves; Input Impedance and Characteristic Impedance; Assessing Afterload from Invasive Hemodynamics; Ventricular Wall Stress Versus Arterial Input Impedance; Afterload Mismatch; Ventriculo-Arterial Coupling and Pressure-Volume Loops; Afterload and Cardiac Efficiency
Definition and Determinants of Cardiac OutputCirculatory Hemodynamics; Hemodynamic Disturbances: The Failing Heart and Shock; Methods of Determining Cardiac Output; Thermodilution; The Fick Cardiac Output; Other Methods of Assessing Cardiac Output; References; Suggested Reading; Part II: Effects of Selected Interventions on CV Hemodynamics; 5: Renin-Angiotensin-Aldosterone Axis Modulators and Other Vasodilators; Introduction; Mechanism of Raas Inhibitors; Cardiovascular Hemodynamics; Angiotensin-Converting Enzyme Inhibitors; Angiotensin Receptor Blockers; Aldosterone Antagonists
Direct Renin InhibitorsDual RAAS Blockade; Other Vasodilators; References; 6: Beta Blockers and Calcium Channel Blockers; Introduction; Beta Blockers; Introduction; Pharmacological Characteristics of Beta Blockers; Hemodynamic Effects of Beta Blockers; Effect on Central Pressure; The Therapeutic Indications of Beta Blockers; Hypertension; Arrhythmia; Heart Failure; Coronary Artery Disease; Conclusion; Calcium Channel Blockers (CCBs); Introduction; Mechanism of Action; Classification; Cardiovascular Hemodynamics; Left Ventricular Hypertrophy; Effects on Cardiac Contractility
Preload in Clinical PracticeInvasive Hemodynamics; Noninvasive Preload Assessment Techniques; Additional Invasive Preload Assessment Techniques; References; Suggested Reading; 2: Afterload; Understanding the Concept; Afterload Physiology and Theory; Afterload and Arterial Vasculature; Reflected Pressure Waves; Input Impedance and Characteristic Impedance; Assessing Afterload from Invasive Hemodynamics; Ventricular Wall Stress Versus Arterial Input Impedance; Afterload Mismatch; Ventriculo-Arterial Coupling and Pressure-Volume Loops; Afterload and Cardiac Efficiency
Definition and Determinants of Cardiac OutputCirculatory Hemodynamics; Hemodynamic Disturbances: The Failing Heart and Shock; Methods of Determining Cardiac Output; Thermodilution; The Fick Cardiac Output; Other Methods of Assessing Cardiac Output; References; Suggested Reading; Part II: Effects of Selected Interventions on CV Hemodynamics; 5: Renin-Angiotensin-Aldosterone Axis Modulators and Other Vasodilators; Introduction; Mechanism of Raas Inhibitors; Cardiovascular Hemodynamics; Angiotensin-Converting Enzyme Inhibitors; Angiotensin Receptor Blockers; Aldosterone Antagonists
Direct Renin InhibitorsDual RAAS Blockade; Other Vasodilators; References; 6: Beta Blockers and Calcium Channel Blockers; Introduction; Beta Blockers; Introduction; Pharmacological Characteristics of Beta Blockers; Hemodynamic Effects of Beta Blockers; Effect on Central Pressure; The Therapeutic Indications of Beta Blockers; Hypertension; Arrhythmia; Heart Failure; Coronary Artery Disease; Conclusion; Calcium Channel Blockers (CCBs); Introduction; Mechanism of Action; Classification; Cardiovascular Hemodynamics; Left Ventricular Hypertrophy; Effects on Cardiac Contractility