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Table of Contents
Introduction: A New Disease?
Section 1 Magnitude of the Problem from an Individual and Social Context
The Dynamics of Diabetes Prevalence, Morbidity and Mortality
Economic Costs, from Individuals to Health Systems: Evidence from a Middle Income Country
The Ecological Approach to Self-Care in Diabetes
Social Determinants of Health and Diabetes Outcomes
Section 2 Diagnosis, Classifications and Mechanisms of Disease
Definition, Diagnostic Criteria, Screening, Diagnosis and Classification of Diabetes and Categories of Glucose Intolerance
Pathophysiology of Type 1 Diabetes
Pathophysiology of Type 2 Diabetes
Genetic Determinants of Type 2 Diabetes
Gene Expression Modifications in Type 2 Diabetes
The Immune System and Inflammation in Type 2 Diabetes
Dysfunction and Death of Pancreatic Beta Cells in Type 2 Diabetes
Obesity in the Pathophysiology of Diabetes
Pathogenesis of Gestational Diabetes
Non-Alcoholic Fatty Liver in the Pathogenesis of Diabetes
Section 3 Global Experiences in Diabetes Care
Diabetes Management in Europe
Diabetes Management in Asia
Diabetes Management in the United States
Diabetes Management in Africa
Section 4 Basic Components of Management: Patient Centeredness, Evidence-Based Medicine and Outcomes. Challenges for Implementation
The Patient-Centered Medical Home, Primary Care and Diabetes
Outpatient Diabetes Management and the Chronic Care Model
Clinical Practice Guidelines for Diabetes
Quality of Diabetes Care: Measuring Clinical Impact, Cost Effectiveness and Patient Experience of Care
Clinical Inertia in Diabetes: The Role of Physicians
Patient Adherence in Diabetes: Challenges, Myths and Realities
Section 5 Resources of Support for Persons with Diabetes
Challenges and Opportunities in Diabetes Education
Diabetes and Mental Health: From Distress to Depression
Tools of Self-Care: Self-Monitoring of Blood Glucose and Tele-health Resources
Continuous Glucose Monitoring and Clinical Decision Making
Diabetes and Lifestyle Medicine
Evidence and Implementation of Nutrition Therapy in Persons with Diabetes
Evidence and Implementation of Physical Activity and Exercise
Section 6 Drug Therapy
The â#x80;Oldâ#x80;#x9D; Oral Antidiabetics
Incretin Therapies: Current Use and Emerging Possibilities
Sodium Glucose Transporter Inhibitors
Insulin in Outpatient Diabetes Management
Insulin Pump Therapy
Section 7 Cardiovascular Risk Factors
Diabetes and Hypertension
Diabetes and Atherogenic Dyslipidemia
Diabetes and Obesity
Diabetes and Smoking
Section 8 Acute Complications
Hyperglycemic Crisis: Diabetic (ketoacidosis (DKA)
Hypoglycemia: Diagnosis, Management and Prevention
Inpatient Management of Diabetes and Hyperglycemia
Diabetes and Infection
Section 9 Chronic Complications
Diabetes and Stroke: The Role of Glucose Regulation
Diabetes and Peripheral Artery Disease
Biochemical and Molecular Mechanisms of Vascular Complications in Diabetes
Ophthalmologic Eye Disease
Diabetes and Oral Health
Renal Disease in Diabetes
Peripheral Diabetic Neuropathies
Diabetic Cardiac Autonomic Neuropathy
Autonomic Visceral Neuropathy and Gastrointestinal Disorders
Urologic Complications and Sexual Dysfunction
Musculoskeletal Complications of Diabetes
Diabetes and the Skin
Foot Complications
Diabetes and Cancer
Section 10 Diabetes in Special Populations
Children and Adolescents
Pregnancy: Pregestational and Gestational Management
The Elderly with Diabetes
Section 11 Diabetes Prevention
Prevention of Type 2 Diabetes: Evidence and Challenges
Section 12 Novel Therapeutic Approaches: Evidence-Based and Others
Insulin Pumps and Closed Loop Systems and the Artificial Pancreas
Unproven Therapies for Diabetes.
Section 1 Magnitude of the Problem from an Individual and Social Context
The Dynamics of Diabetes Prevalence, Morbidity and Mortality
Economic Costs, from Individuals to Health Systems: Evidence from a Middle Income Country
The Ecological Approach to Self-Care in Diabetes
Social Determinants of Health and Diabetes Outcomes
Section 2 Diagnosis, Classifications and Mechanisms of Disease
Definition, Diagnostic Criteria, Screening, Diagnosis and Classification of Diabetes and Categories of Glucose Intolerance
Pathophysiology of Type 1 Diabetes
Pathophysiology of Type 2 Diabetes
Genetic Determinants of Type 2 Diabetes
Gene Expression Modifications in Type 2 Diabetes
The Immune System and Inflammation in Type 2 Diabetes
Dysfunction and Death of Pancreatic Beta Cells in Type 2 Diabetes
Obesity in the Pathophysiology of Diabetes
Pathogenesis of Gestational Diabetes
Non-Alcoholic Fatty Liver in the Pathogenesis of Diabetes
Section 3 Global Experiences in Diabetes Care
Diabetes Management in Europe
Diabetes Management in Asia
Diabetes Management in the United States
Diabetes Management in Africa
Section 4 Basic Components of Management: Patient Centeredness, Evidence-Based Medicine and Outcomes. Challenges for Implementation
The Patient-Centered Medical Home, Primary Care and Diabetes
Outpatient Diabetes Management and the Chronic Care Model
Clinical Practice Guidelines for Diabetes
Quality of Diabetes Care: Measuring Clinical Impact, Cost Effectiveness and Patient Experience of Care
Clinical Inertia in Diabetes: The Role of Physicians
Patient Adherence in Diabetes: Challenges, Myths and Realities
Section 5 Resources of Support for Persons with Diabetes
Challenges and Opportunities in Diabetes Education
Diabetes and Mental Health: From Distress to Depression
Tools of Self-Care: Self-Monitoring of Blood Glucose and Tele-health Resources
Continuous Glucose Monitoring and Clinical Decision Making
Diabetes and Lifestyle Medicine
Evidence and Implementation of Nutrition Therapy in Persons with Diabetes
Evidence and Implementation of Physical Activity and Exercise
Section 6 Drug Therapy
The â#x80;Oldâ#x80;#x9D; Oral Antidiabetics
Incretin Therapies: Current Use and Emerging Possibilities
Sodium Glucose Transporter Inhibitors
Insulin in Outpatient Diabetes Management
Insulin Pump Therapy
Section 7 Cardiovascular Risk Factors
Diabetes and Hypertension
Diabetes and Atherogenic Dyslipidemia
Diabetes and Obesity
Diabetes and Smoking
Section 8 Acute Complications
Hyperglycemic Crisis: Diabetic (ketoacidosis (DKA)
Hypoglycemia: Diagnosis, Management and Prevention
Inpatient Management of Diabetes and Hyperglycemia
Diabetes and Infection
Section 9 Chronic Complications
Diabetes and Stroke: The Role of Glucose Regulation
Diabetes and Peripheral Artery Disease
Biochemical and Molecular Mechanisms of Vascular Complications in Diabetes
Ophthalmologic Eye Disease
Diabetes and Oral Health
Renal Disease in Diabetes
Peripheral Diabetic Neuropathies
Diabetic Cardiac Autonomic Neuropathy
Autonomic Visceral Neuropathy and Gastrointestinal Disorders
Urologic Complications and Sexual Dysfunction
Musculoskeletal Complications of Diabetes
Diabetes and the Skin
Foot Complications
Diabetes and Cancer
Section 10 Diabetes in Special Populations
Children and Adolescents
Pregnancy: Pregestational and Gestational Management
The Elderly with Diabetes
Section 11 Diabetes Prevention
Prevention of Type 2 Diabetes: Evidence and Challenges
Section 12 Novel Therapeutic Approaches: Evidence-Based and Others
Insulin Pumps and Closed Loop Systems and the Artificial Pancreas
Unproven Therapies for Diabetes.