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Table of Contents
Sex differences in disease
Evolution of the human sex chromosomes and a portrait of the human X
X chromosome dosage compensation : an overview
The discovery of X chromosome inactivation
Experimental models for X inactivation studies
Theme 1 : the initial step : creating the active and inactive X
Theme 2 : subsequent steps : spreading and maintaining inactivation
Variations 1 : evolution of the X inactivation center
Variations 2 : stability of the inactive X
Variations 3 : choice of active X
The single active X
Mosaicism
Epimutations, chromatin disorders and sex differences in phenotype
Determinants of female phenotypes.
Evolution of the human sex chromosomes and a portrait of the human X
X chromosome dosage compensation : an overview
The discovery of X chromosome inactivation
Experimental models for X inactivation studies
Theme 1 : the initial step : creating the active and inactive X
Theme 2 : subsequent steps : spreading and maintaining inactivation
Variations 1 : evolution of the X inactivation center
Variations 2 : stability of the inactive X
Variations 3 : choice of active X
The single active X
Mosaicism
Epimutations, chromatin disorders and sex differences in phenotype
Determinants of female phenotypes.