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000913073 019__ $$a1110240874$$a1114172732$$a1114935355$$a1117334912$$a1119481982$$a1119779276
000913073 020__ $$a9783030160821$$q(electronic book)
000913073 020__ $$a3030160823$$q(electronic book)
000913073 0248_ $$a10.1007/978-3-030-16
000913073 0247_ $$a10.1007/978-3-030-16082-1$$2doi
000913073 035__ $$aSP(OCoLC)on1110486583
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000913073 049__ $$aISEA
000913073 050_4 $$aRC337$$b.A55 2019
000913073 08204 $$a612.8$$223
000913073 24500 $$aAnimal models of acute neurological injury /$$cJun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors.
000913073 250__ $$aSecond edition.
000913073 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2019]
000913073 300__ $$a1 online resource
000913073 336__ $$atext$$btxt$$2rdacontent
000913073 337__ $$acomputer$$bc$$2rdamedia
000913073 338__ $$aonline resource$$bcr$$2rdacarrier
000913073 347__ $$atext file$$bPDF$$2rda
000913073 4901_ $$aSpringer series in translational stroke research
000913073 500__ $$aIncludes index.
000913073 5050_ $$aIntro; Preface; Contents; Part I: Animal Care and Surgery; Animal Protocol; Regulatory Oversight; Designing the Animal Protocol; Writing the Animal Protocol; References; Anesthesia and Analgesia for Research Animals; Introduction; Pre-anesthetic Considerations and Monitoring; Injectable Anesthetics; Bartiturates; Ketamine; Propofol; Sedative/Tranquilizers; Local Anesthetics; Gaseous Agents; Isoflurane; Sevoflurane; Other Inhalants; Hypothermia; Analgesia; Opioids; Non-steroidal Anti-inflammatory Drugs (NSAIDs); Other Analgesics
000913073 5058_ $$aSpecial Considerations-Anesthesia and Analgesia for Animal Models of Neurologic DiseasesCerebral Ischemia and Hemorrhage Models; Physiologic Effects of Anesthesia and the Impact on Cerebral Ischemia and Hemorrhage Models; Anesthetic Considerations; Analgesic Considerations; Traumatic Brain Injury Models; Anesthetic Considerations; Analgesic Considerations; Spinal Cord Injury Models; Physiologic Effects of Anesthesia and the Impact on SCI Models; Anesthetic and Analgesic Agents Impact Spinal Injury Models; References; Rodent Surgical Procedures and Tissue Collection; Introduction
000913073 5058_ $$aAirway Management in the Rodent ModelIntubation; Materials; Procedures; Transcardiac Perfusion and Fixation; Equipment and Materials; Step by Step Procedures; Methods of Brain Removal; Materials; Procedures; Brain Removal; Separation of the Brain into Anatomical Sections; Materials; Procedure; Preparation of Brain Slices for Triphenyltetrazolium Chloride Staining; Materials; Procedure; References; Brain Monitoring; Introduction; Model Selection; Materials; Intravenous Femoral Catheter; Procedure; Burr Hole and Brain Monitoring; Postoperative Care; Conclusion; References
000913073 5058_ $$aVeterinary Care Methods for Rats and Mice in Experimental Spinal Cord Injury Studies: An UpdateModel Selection; Materials and Methods; Before Surgery and SCI; Surgery and SCI; Sterilization; Preparation; Surgery and SCI; Acutely and the First Week After Surgery and SCI; Housing; Veterinary Care; Chronically After Surgery and SCI; References; Part II: Cerebral Ischemic Animal Models; Four-Vessel Occlusion Model in Rats; Model Selection; Materials; Animal; Anesthesia; Equipment; Anesthesia; Surgery; Recording of Ischemic Depolarization; Procedures; Original 4-VO Model
000913073 5058_ $$aPlacement of Occluding Device Around Carotid ArteryElectrocauterization of Vertebral Artery; Occlusion of Bilateral Common Carotid Arteries; One-Day 4-VO Model (with ID Recording); Surgical Preparation; ID Recording; Outcome Evaluation; Ischemic Cell Death in the Hippocampus; Ischemic Cell Death in the Striatum; Advantages, Complications and Limitations; Advantages; Complications; Limitations; Technical Difficulties; Mortality; Variation; References; Rat Model of Global Cerebral Ischemia: The Two-Vessel Occlusion (2VO) Model of Forebrain Ischemia; Introduction
000913073 506__ $$aAccess limited to authorized users.
000913073 520__ $$aDespite numerous recent studies and exciting discoveries in the field, only limited treatments are available today for the victims of acute brain and spinal cord injuries. Animal Models of Acute Neurological Injuries, Second Edition, provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that often inhibit advances in this specialized research field. In the 10 years since publication of the first edition of this book, some animal models have become obsolete, some have stood the test of time, and newer models have emerged to enhance our knowledge of acute neurological injuries. The second edition continues to offer the research community tested approaches for this area of investigation. As with the first edition, top experts have developed and contributed these animal models. The books focus remains hands-on, practical applications of the models, rather than a theoretical approach. Each chapter contains a proven procedure enhanced by clear figures, illustrations, or videos. This new edition presents its readily reproducible protocols with clarity and consistency to best aid neuroscientists and neurobiologists. As with the first edition, the second edition is comprehensive and cutting-edge. Animal Models of Acute Neurological Injuries, Second Edition, is an ideal guide for research professionals, at all stages of their careers, who wish to pursue this vital course of study with the proficiency and precision required by the field.
000913073 588__ $$aDescription based on online resource; title from digital title page (viewed on September 13, 2019).
000913073 650_0 $$aNervous system$$xDiseases$$xAnimal models$$vHandbooks, manuals, etc.
000913073 650_0 $$aNervous system$$xWounds and injuries$$vHandbooks, manuals, etc.
000913073 650_0 $$aNervous system$$xPathophysiology$$xAnimal models$$vHandbooks, manuals, etc.
000913073 7001_ $$aChen, Jun,$$eeditor.
000913073 7001_ $$aXu, Zao C.,$$eeditor.
000913073 7001_ $$aXu, Xiao-Ming,$$eeditor.
000913073 7001_ $$aZhang, J. H.$$q(John H.),$$eeditor.
000913073 77608 $$iPrint version:$$aChen, Jun.$$tAnimal Models of Acute Neurological Injury.$$dCham : Springer, ©2019$$z9783030160807
000913073 830_0 $$aSpringer series in translational stroke research.
000913073 852__ $$bebk
000913073 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-16082-1$$zOnline Access$$91397441.1
000913073 909CO $$ooai:library.usi.edu:913073$$pGLOBAL_SET
000913073 980__ $$aEBOOK
000913073 980__ $$aBIB
000913073 982__ $$aEbook
000913073 983__ $$aOnline
000913073 994__ $$a92$$bISE