Fluorescence lifetime imaging ophthalmoscopy / Martin Zinkernagel, Chantal Dysli.
Zinkernagel, Martin, editor.; Dysli, Chantal, editor.
2019
RE78 .F58 2019
Available Online

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Title
Fluorescence lifetime imaging ophthalmoscopy / Martin Zinkernagel, Chantal Dysli.
ISBN
9783030228781 (electronic book)
3030228789 (electronic book)
9783030228774
3030228770
9783030228798
3030228797
9783030228804
3030228800
DOI
https://doi.org/10.1007/978-3-030-22878-1
Published
Cham, Switzerland : Springer, [2019]
Language
English
Description
1 online resource
Item Number
10.1007/978-3-030-22878-1 doi
10.1007/978-3-030-22
Call Number
RE78 .F58 2019
Dewey Decimal Classification
617.7/1
Summary
This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.
Note
Includes index.
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Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Description based on online resource; title from digital title page (viewed on September 13, 2019).
Added Author
Zinkernagel, Martin, editor.
Dysli, Chantal, editor.
Available in Other Form
Fluorescence Lifetime Imaging Ophthalmoscopy.
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Intro; Foreword; Chapter 1: Introduction; References; Chapter 2: FLIO Technique and Principles; References; Chapter 3: FLIO Historical Background; References; Chapter 4: Fluorescence Lifetime Imaging Microscopy; References; Chapter 5: The Fluorescence Lifetime Imaging Ophthalmoscope; References; Chapter 6: Image Acquisition and Analysis; FLIO Reader; FLIMX; Supplementary Material; FLIO Image Acquisition Protocol; Subjects; Measurement; Preparation; Before Image Acquisition; During Measurement

End of AcquisitionReferences; Chapter 7: Fluorophores in the Eye; Introduction; Lipofuscin (Bisretinoids); Xantophyll (Yellow Carotinoids): Macular Pigment; Collagen/Elastin; Redox Coenzyme; Melanin/Oxidized Melanin; Lipid Peroxidation Endproducts; Advanced Glycation Endproducts (AGE); Other Fluorophores; References; Chapter 8: FLIO in the Healthy Eye; References; Chapter 9: FLIO in Retinal Diseases; References; Chapter 10: Age-Related Macular Degeneration; FLIO in Early Disease Stages of AMD; FLIO in AMD with Drusen; FLIO in Geographic Atrophy; References

Chapter 11: FLIO in Diabetic RetinopathyReferences; Chapter 12: Retinal Artery Occlusion; References; Chapter 13: Central Serous Chorioretinopathy; References; Chapter 14: Macular Telangiectasia Type 2; References; Chapter 15: Hereditary Retinal Diseases: Stargardt, Choroideremia, Retinitis Pigmentosa; Stargardt Disease; Choroideremia; Retinitis Pigmentosa; References; Chapter 16: Macular Pigment; Retinal Carotenoids; Carotenoid Measurement Ex Vivo; Macular Holes; Albinism; References; Chapter 17: Fluorescence Lifetime Imaging Ophthalmoscopy in Alzheimer's Disease; References

Chapter 18: FLIO in Mouse ModelsReferences; Chapter 19: Discussion and Summary; Index

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