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Title
Pot, atom, and step economy (PASE) synthesis / Wei Zhang, Wen-Bin Yi.
ISBN
9783030225964
3030225968
Publication Details
Cham : Springer, [2019]
Language
English
Description
1 online resource (55 pages).
Call Number
QD262
Dewey Decimal Classification
547.2
Summary
This book emphasizes the atom economy aspect of multicomponent reactions. It describes how this methodology has been applied to several named reactions. Among the "twelve principles of green chemistry", atom economy addresses 'synthetic efficiency. A multicomponent reaction can be defined as an energy, cost, and time efficient method for organic synthesis. Instead of making one or two bonds in a chemical transformation, multicomponent reactions generate several chemical bonds in a single operation. This book presents a series of detailed reaction mechanisms that beautifully illustrate this principle. Multicomponent reactions are widely applied to the preparation of complex and diverse molecular structures in academic and industrial research laboratories. As such, this book is targeted at researchers involved in green organic chemistry.
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Source of Description
Description based on print version record.
Series
SpringerBriefs in molecular science.
SpringerBriefs in molecular science. Green chemistry for sustainability.
Intro; Preface; Contents; Abbreviations; 1 Introduction to PASE Synthesis; References; 2 One-Pot Reactions; 2.1 Introduction; 2.2 One-Pot Non-catalytic Reactions; 2.3 One-Pot Catalytic Reactions; 2.4 One-Pot Cycloaddition Reactions; References; 3 Cascade Reactions; 3.1 Introduction; 3.2 Cascade Ionic Reactions; 3.3 Cascade Transition Metal-Catalyzed Reactions; 3.4 Cascade Pericyclic Reactions; 3.5 Cascade Radical Reactions; References; 4 Multicomponent Reactions (MCRs); 4.1 Introduction; 4.2 Direct MCRs; 4.3 High-Order MCRs; 4.4 MCRs Followed by Post-condensation Modifications
4.5 Consecutive MCRsReferences; 5 Applications of PASE Synthesis; 5.1 Introduction; 5.2 PASE Synthesis in Medicinal Chemistry; 5.3 PASE Synthesis in Natural Product Synthesis; References; 6 Conclusive Remarks
