000913279 000__ 03014cam\a2200445Ia\4500 000913279 001__ 913279 000913279 005__ 20230306150420.0 000913279 006__ m\\\\\o\\d\\\\\\\\ 000913279 007__ cr\cn\nnnunnun 000913279 008__ 190817s2019\\\\si\\\\\\o\\\\\000\0\eng\d 000913279 019__ $$a1117282733$$a1117698135 000913279 020__ $$a9789811388712$$q(electronic book) 000913279 020__ $$a9811388717$$q(electronic book) 000913279 020__ $$z9789811388705 000913279 0247_ $$a10.1007/978-981-13-8 000913279 035__ $$aSP(OCoLC)on1112423702 000913279 035__ $$aSP(OCoLC)1112423702$$z(OCoLC)1117282733$$z(OCoLC)1117698135 000913279 040__ $$aEBLCP$$beng$$cEBLCP$$dN$T$$dEBLCP$$dGW5XE$$dUIU$$dLQU$$dUKMGB 000913279 049__ $$aISEA 000913279 050_4 $$aRC903.9 000913279 08204 $$a616.6/107$$223 000913279 24500 $$aRenal fibrosis :$$bmechanisms and therapies /$$cBi-Cheng Liu, Hui-Yao Lan, Lin-Li Lv, editors. 000913279 260__ $$aSingapore :$$bSpringer,$$c2019. 000913279 300__ $$a1 online resource (707 pages). 000913279 336__ $$atext$$btxt$$2rdacontent 000913279 337__ $$acomputer$$bc$$2rdamedia 000913279 338__ $$aonline resource$$bcr$$2rdacarrier 000913279 4901_ $$aAdvances in experimental medicine and biology ;$$v1165 000913279 506__ $$aAccess limited to authorized users. 000913279 520__ $$aThis book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions. 000913279 588__ $$aOnline resource; title from PDF title page (viewed August 21, 2019) 000913279 650_0 $$aKidneys$$xFibrosis. 000913279 7001_ $$aLiu, Bi-Cheng. 000913279 7001_ $$aLan, Hui-Yao. 000913279 7001_ $$aLv, Lin-Li. 000913279 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1165. 000913279 852__ $$bebk 000913279 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-13-8871-2$$zOnline Access$$91397441.1 000913279 909CO $$ooai:library.usi.edu:913279$$pGLOBAL_SET 000913279 980__ $$aEBOOK 000913279 980__ $$aBIB 000913279 982__ $$aEbook 000913279 983__ $$aOnline 000913279 994__ $$a92$$bISE