000913298 000__ 04741cam\a2200529Ii\4500 000913298 001__ 913298 000913298 005__ 20230306150421.0 000913298 006__ m\\\\\o\\d\\\\\\\\ 000913298 007__ cr\un\nnnunnun 000913298 008__ 190824s2019\\\\sz\\\\\\ob\\\\000\0\eng\d 000913298 019__ $$a1113370425$$a1114364504 000913298 020__ $$a9783030195151$$q(electronic book) 000913298 020__ $$a3030195155$$q(electronic book) 000913298 020__ $$z3030195147 000913298 020__ $$z9783030195144 000913298 035__ $$aSP(OCoLC)on1112424985 000913298 035__ $$aSP(OCoLC)1112424985$$z(OCoLC)1113370425$$z(OCoLC)1114364504 000913298 040__ $$aEBLCP$$beng$$cEBLCP$$dYDX$$dGW5XE 000913298 049__ $$aISEA 000913298 050_4 $$aRC600 000913298 08204 $$a616.978$$223 000913298 24500 $$aNeuroimmune diseases :$$bfrom cells to the living brain /$$cHiroshi Mitoma, Mario Manto, editors. 000913298 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2019] 000913298 300__ $$a1 online resource (819 pages). 000913298 336__ $$atext$$btxt$$2rdacontent 000913298 337__ $$acomputer$$bc$$2rdamedia 000913298 338__ $$aonline resource$$bcr$$2rdacarrier 000913298 4901_ $$aContemporary clinical neuroscience 000913298 504__ $$aIncludes bibliographical references. 000913298 5050_ $$aIntro; Contents; Part I: Fundamental Mechanisms and General Principles; Overview of Mechanisms Underlying Neuroimmune Diseases; Introduction; Divergence and Convergence in Neuroimmune Diseases; Blood-Brain Barrier and Blood-Nerve Barrier; Local Immune Cascades; Therapeutic Strategies of Neuroimmune Diseases; Clinical Features of Neuroimmune Diseases; Lesion-Dependent Neurological Symptoms; Association of Other Neuroimmune Diseases; Multifocal Lesions; Divergent Immune Mechanisms; Fundamental Pathogenic Factors Determining Clinical Profiles; Autoantibody- and Cell-Mediated Immune Mechanisms 000913298 5058_ $$aNeuroinflammatory CascadesTriggering of Autoimmunity: Parainfectious and Paraneoplastic Conditions; Cross Talk Between the Immune System and Degenerative or Psychiatric Diseases; Mechanisms of Neuroimmune Diseases; Mechanisms of T Cell-Mediated Neuroinflammation and Autoimmunity; Mechanisms of Antibody-Mediated Neuroinflammation and Autoimmunity; Role of Infections in the Neuroinflammation and Autoimmunity; Neuroimmune Mechanisms in Paraneoplastic Diseases; Neuroimmune Mechanisms in Vascular Inflammatory Diseases; Neuroimmune Mechanisms in Neurodegenerative Diseases 000913298 5058_ $$aNeuroimmune Mechanisms in Neuropsychiatric DiseasesFuture Perspective; References; Roles of Effector T Cells in Neurological Autoimmunity; Introduction; Dysregulation of the Th1/Th2 Balance in MS; Th17 Cells in MS/EAE; CD8 T Cells in MS/EAE; Possible Therapeutic Targets for Neurodegeneration and Demyelination in MS and EAE; Conclusion; References; The Role of Th17 Cells in Immunopathogenesis of Neuroinflammatory Disorders; Introduction; The Role of Th17 Cells in Immunopathogenesis of Multiple Sclerosis; Roles of Th1 and Th17 Cells in Pathogenesis of Multiple Sclerosis 000913298 5058_ $$aActions of Divergent Pro-Inflammatory CytokinesTh17 Cell Plasticity; Multiple Actions of IL-17; Th17-Related Inflammation and the Neuronal Apoptosis; Multiple Actions of IL-22, IL-23, and GM-CSF; Open Problems and Therapeutic Applications; The Role of Th17 Cells in Immunopathogenesis of Alzheimer Disease; Link Between Immune System and Neurodegeneration; Th17-Mediated Mechanisms in Alzheimer Disease; The Role of Th17 Cells in Immunopathogenesis of Parkinson Disease; Immune-Mediated Mechanisms in Parkinson Disease; Th17 Cell Role in Parkinson Disease 000913298 5058_ $$aThe Role of Th17 Cells in Immunopathogenesis of Schizophrenia DiseaseImmunopathology of Schizophrenia Disease; Immunopathology of Schizophrenia from Th17 Cell Viewpoint; Conclusion; References; Significance of Autoantibodies; Introduction; Theme A: Causes of Antibody Development; Paraneoplastic Neurologic Disorders (PNS); Clinical Example; Anti-Yo Antibody-Associated Paraneoplastic Cerebellar Degenerations; Infection; Clinical Example; Herpes Simplex Virus-1 (HSV-1) Encephalitis and NMDAR Encephalitis; Injuries to the CNS; Clinical Example; Long-Term Neurological and Systemic Complications in SCI Patients 000913298 506__ $$aAccess limited to authorized users. 000913298 588__ $$aDescription based on print version record. 000913298 650_0 $$aAutoimmune diseases. 000913298 650_0 $$aNervous system$$xDiseases. 000913298 650_0 $$aNeuroimmunology. 000913298 7001_ $$aMitoma, Hiroshi,$$eeditor. 000913298 7001_ $$aManto, Mario,$$eeditor. 000913298 77608 $$iPrint version:$$aMitoma, Hiroshi$$tNeuroimmune Diseases : From Cells to the Living Brain$$dCham : Springer,c2019$$z9783030195144 000913298 830_0 $$aContemporary clinical neuroscience. 000913298 852__ $$bebk 000913298 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-19515-1$$zOnline Access$$91397441.1 000913298 909CO $$ooai:library.usi.edu:913298$$pGLOBAL_SET 000913298 980__ $$aEBOOK 000913298 980__ $$aBIB 000913298 982__ $$aEbook 000913298 983__ $$aOnline 000913298 994__ $$a92$$bISE