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000913409 019__ $$a1117286782$$a1117701120
000913409 020__ $$a9783030280420$$q(electronic book)
000913409 020__ $$a303028042X$$q(electronic book)
000913409 020__ $$z9783030280413
000913409 020__ $$a3030280411
000913409 020__ $$a9783030280413
000913409 0247_ $$a10.1007/978-3-030-28042-0$$2doi
000913409 0247_ $$a10.1007/978-3-030-28
000913409 035__ $$aSP(OCoLC)on1114330294
000913409 035__ $$aSP(OCoLC)1114330294$$z(OCoLC)1117286782$$z(OCoLC)1117701120
000913409 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dLQU$$dUPM$$dUKMGB
000913409 049__ $$aISEA
000913409 050_4 $$aQA76.9.L63$$bH73 2019eb
000913409 08204 $$a005.101/5113$$223
000913409 1112_ $$aHSB (Workshop)$$n(6th :$$d2019 :$$cPrague, Czech Republic)
000913409 24510 $$aHybrid systems biology :$$b6th International Workshop, HSB 2019, Prague, Czech Republic, April 6-7, 2019 : revised selected papers /$$cMilan Češka, Nicola Paoletti (eds.).
000913409 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2019]
000913409 300__ $$a1 online resource (xvi, 181 pages) :$$billustrations.
000913409 336__ $$atext$$btxt$$2rdacontent
000913409 337__ $$acomputer$$bc$$2rdamedia
000913409 338__ $$aonline resource$$bcr$$2rdacarrier
000913409 4901_ $$aLecture notes in bioinformatics,$$x1611-3349 ;$$v11705
000913409 4901_ $$aLNCS sublibrary: SL 8 --  Bioinformatics
000913409 504__ $$aIncludes bibliographical references and index.
000913409 5050_ $$aA multimodular system to study the impact of a focal lesion in neuronal cell cultures -- Reachability analysis and hybrid systems biology -- In Memoriam Oded Maler -- Reaction networks, oscillatory motifs and parameter estimation in biochemical systems -- Fixed-point computation of equilibria in biochemical regulatory networks -- Rejection-based simulation of stochastic spreading processes on complex networks -- Controlling noisy expression through auto regulation of burst frequency and protein stability -- Extracting landscape features from single particle trajectories -- A hybrid HMM approach for the dynamics of DNA methylation -- Using a hybrid approach to model central carbon metabolism across the cell cycle -- Data-informed parameter synthesis for population Markov chains-. rPrism -- A software for reactive weighted state transition models -- Hybrid modeling of metabolic-regulatory networks.
000913409 506__ $$aAccess limited to authorized users.
000913409 520__ $$aThis book constitutes the thoroughly refereed proceedings of the 6th International Workshop on Hybrid Systems Biology, HSB 2019, held in Prague, Czech Republic, in April 2019. The 8 full papers presented in this book together with 1 short paper and 3 invited papers were carefully reviewed and selected from 13 submissions. They cover topics such as: modeling and analysis of metabolic, signaling, and genetic regulatory networks in living cells; models of tissues, organs, physiological models; models and methods coping with incomplete, uncertain and heterogeneous information including learning for biological systems, parametric synthesis and inference; stochastic and hybrid models in biology; hierarchical systems for multi-scale, multi-domain analysis; abstraction, approximation, discretization, and model reduction techniques; modeling, analysis and design for synthetic biology, cyber-biological systems and biomedical studies (e.g. therapies, teleoperation); game-theoretical frameworks and population models in biology (e.g. mixed-effects and Bayesian modeling); biological applications of quantitative and formal analysis techniques (e.g. reachability computation, model checking, abstract interpretation, bifurcation theory, stability and sensitivity analysis); efficient techniques for combined and heterogeneous (stochastic/deterministic, spatial/non-spatial) simulations for biological models; modeling languages and logics for biological systems with related analysis and simulation tools; and control architectures of biological systems including biology-in-the-loop systems and bio-robotics.
000913409 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 29, 2019).
000913409 650_0 $$aSystems biology$$vCongresses.
000913409 650_0 $$aHybrid systems$$vCongresses.
000913409 7001_ $$aČeška, M.$$q(Milan),$$eeditor.
000913409 7001_ $$aPaoletti, Nicola,$$eeditor.
000913409 830_0 $$aLNCS sublibrary.$$nSL 8,$$pBioinformatics.
000913409 830_0 $$aLecture notes in computer science.$$pLecture notes in bioinformatics ;$$v11705.
000913409 852__ $$bebk
000913409 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-28042-0$$zOnline Access$$91397441.1
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