TY  - GEN
AB  - This book illustrates the activities of mammalian sirtuin SIRT6 in connection with DNA damage repair and premature aging. It mainly presents research on the nuclear lamin A, notably the upregulation of p53 and acetylation etc. Taken together, these studies reveal the various regulatory roles of SIRT6, which are of substantial biological relevance in DNA damage repair, aging and longevity, and can have significant implications in devising therapeutic strategies to combat age-associated pathologies. Given its scope, the book offers a valuable resource for students and researchers in the fields of genetics, cell biology, molecular biology etc.
AU  - Ghosh, Shrestha,
CN  - QH467
DO  - 10.1007/978-981-32-9267-3
DO  - doi
ID  - 913785
KW  - Sirtuins.
KW  - DNA repair.
KW  - Aging
LK  - https://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-32-9267-3
N1  - "Doctoral thesis accepted by The University of Hong Kong, Hong Kong, China."
N2  - This book illustrates the activities of mammalian sirtuin SIRT6 in connection with DNA damage repair and premature aging. It mainly presents research on the nuclear lamin A, notably the upregulation of p53 and acetylation etc. Taken together, these studies reveal the various regulatory roles of SIRT6, which are of substantial biological relevance in DNA damage repair, aging and longevity, and can have significant implications in devising therapeutic strategies to combat age-associated pathologies. Given its scope, the book offers a valuable resource for students and researchers in the fields of genetics, cell biology, molecular biology etc.
SN  - 9789813292673
SN  - 9813292679
T1  - SIRT6 activities in DNA damage repair and premature aging :functions of SIRT6 /
TI  - SIRT6 activities in DNA damage repair and premature aging :functions of SIRT6 /
UR  - https://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-32-9267-3
ER  -