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000914516 019__ $$a1121266226
000914516 020__ $$a9783030220945$$q(electronic book)
000914516 020__ $$a303022094X$$q(electronic book)
000914516 020__ $$z9783030220938
000914516 0247_ $$a10.1007/978-3-030-22
000914516 035__ $$aSP(OCoLC)on1119627091
000914516 035__ $$aSP(OCoLC)1119627091$$z(OCoLC)1121266226
000914516 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dLQU$$dOCLCF
000914516 049__ $$aISEA
000914516 050_4 $$aRC582
000914516 08204 $$a616.97$$223
000914516 24500 $$aCytokine storm syndrome /$$cRandy Q. Cron, Edward M. Behrens, editors.
000914516 260__ $$aCham :$$bSpringer,$$c2019.
000914516 300__ $$a1 online resource (607 pages)
000914516 336__ $$atext$$btxt$$2rdacontent
000914516 337__ $$acomputer$$bc$$2rdamedia
000914516 338__ $$aonline resource$$bcr$$2rdacarrier
000914516 504__ $$aIncludes bibliographical references and index.
000914516 506__ $$aAccess limited to authorized users.
000914516 520__ $$aCytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals. A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This textbook, the first of its kind, addresses all aspects of the disorder – from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors, and treatment.
000914516 588__ $$aDescription based on print version record.
000914516 650_0 $$aImmunologic diseases.
000914516 650_0 $$aCytokines.
000914516 7001_ $$aCron, Randy Q.
000914516 7001_ $$aBehrens, Edward M.
000914516 77608 $$iPrint version:$$aCron, Randy Q.$$tCytokine Storm Syndrome$$dCham : Springer,c2019$$z9783030220938
000914516 852__ $$bebk
000914516 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-22094-5$$zOnline Access$$91397441.1
000914516 909CO $$ooai:library.usi.edu:914516$$pGLOBAL_SET
000914516 980__ $$aEBOOK
000914516 980__ $$aBIB
000914516 982__ $$aEbook
000914516 983__ $$aOnline
000914516 994__ $$a92$$bISE