Fc mediated activity of antibodies : structural and functional diversity / Jeffrey V. Ravetch, Falk Nimmerjahn.
Ravetch, J. V. (Jeffrey V.), 1951-; Nimmerjahn, Falk.
2019
QR185.8.F33
Available Online

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Title Fc mediated activity of antibodies : structural and functional diversity / Jeffrey V. Ravetch, Falk Nimmerjahn.
ISBN 9783030310530 (electronic book)
3030310531 (electronic book)
DOI https://doi.org/10.1007/978-3-030-31
Publication Details Cham : Springer, 2019.
Language English
Description 1 online resource (155 pages).
Item Number 10.1007/978-3-030-31
Call Number QR185.8.F33
Dewey Decimal Classification 616.079
Summary This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed September 20, 2019).
Added Author Ravetch, J. V. (Jeffrey V.), 1951-
Nimmerjahn, Falk.
Series Current topics in microbiology and immunology ; 423.
Available in Other Form Fc Mediated Activity of Antibodies : Structural and Functional Diversity
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
All Resources
IgG Fc receptors: evolutionary considerations
Role of FcgRs in Antibody Based Cancer Therapy
Anti-inflammatory Activity of IgG-Fc
IgG Fc glycosylation in human immunity
IgE Glycosylation in Health and Disease
Immune Complex Vaccination
Fc receptors in anti-microbial protection.

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