000914570 000__ 03471cam\a2200457Ia\4500 000914570 001__ 914570 000914570 005__ 20230306150358.0 000914570 006__ m\\\\\o\\d\\\\\\\\ 000914570 007__ cr\un\nnnunnun 000914570 008__ 190914s2019\\\\sz\\\\\\o\\\\\000\0\eng\d 000914570 019__ $$a1121271185 000914570 020__ $$a9783030211622 000914570 020__ $$a3030211622 000914570 020__ $$z9783030211615 000914570 0247_ $$a10.1007/978-3-030-21 000914570 035__ $$aSP(OCoLC)on1119642639 000914570 035__ $$aSP(OCoLC)1119642639$$z(OCoLC)1121271185 000914570 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dLQU$$dOCLCF 000914570 049__ $$aISEA 000914570 050_4 $$aQP752.C37 000914570 08204 $$a572/.57$$223 000914570 24500 $$aBioactive Ceramides in Health and Disease :$$bIntertwined Roles of Enigmatic Lipids /$$cJohnny Stiban, editor. 000914570 260__ $$aCham :$$bSpringer,$$c2019. 000914570 300__ $$a1 online resource (159 pages). 000914570 336__ $$atext$$btxt$$2rdacontent 000914570 337__ $$acomputer$$bc$$2rdamedia 000914570 338__ $$aonline resource$$bcr$$2rdacarrier 000914570 4901_ $$aAdvances in Experimental Medicine and Biology ;$$vv.1159 000914570 500__ $$aIncludes index. 000914570 506__ $$aAccess limited to authorized users. 000914570 520__ $$aThis book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented. Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry. World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings. This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations. 000914570 588__ $$aDescription based on print version record. 000914570 650_0 $$aCeramides. 000914570 650_0 $$aBioactive compounds. 000914570 7001_ $$aStiban, Johnny. 000914570 77608 $$iPrint version:$$aStiban, Johnny$$tBioactive Ceramides in Health and Disease : Intertwined Roles of Enigmatic Lipids$$dCham : Springer,c2019$$z9783030211615 000914570 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1159. 000914570 852__ $$bebk 000914570 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-21162-2$$zOnline Access$$91397441.1 000914570 909CO $$ooai:library.usi.edu:914570$$pGLOBAL_SET 000914570 980__ $$aEBOOK 000914570 980__ $$aBIB 000914570 982__ $$aEbook 000914570 983__ $$aOnline 000914570 994__ $$a92$$bISE