Biophysics of RNA-protein interactions : a mechanistic view / Chirlmin Joo, David Rueda, editors.
Joo, Chirlmin, editor.; Rueda, David, editor.
2019
QP623.8.P75
Available Online

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Title
Biophysics of RNA-protein interactions : a mechanistic view / Chirlmin Joo, David Rueda, editors.
ISBN
9781493997268 (electronic book)
1493997262 (electronic book)
9781493997244
DOI
https://doi.org/10.1007/978-1-4939-9726-8
https://doi.org/10.1007/978-1-4939-9
Published
New York, NY : Springer, 2019.
Language
English
Description
1 online resource (vii, 249 pages) : illustrations.
Item Number
10.1007/978-1-4939-9726-8 doi
10.1007/978-1-4939-9
Call Number
QP623.8.P75
Dewey Decimal Classification
572.8/8
Summary
RNA molecules play key roles in all aspects of cellular life, but to do so efficiently, they must work in synergism with proteins. This book addresses how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more. The topics addressed in this volume will appeal to researchers in biophysics, biochemistry and structural biology. The book is a useful resource for anybody interested in elucidating the molecular mechanisms and discrete properties of RNA-protein complexes. Included are reviews of key systems such as microRNA and CRISPR/Cas that exemplify how RNA and proteins work together to perform their biological function. Also covered are techniques ranging from single molecule fluorescence and force spectroscopy to crystallography, cryo-EM microscopy, and kinetic modeling.
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed September 26, 2019).
Added Author
Joo, Chirlmin, editor.
Rueda, David, editor.
Series
Biological and medical physics, biomedical engineering.
Available in Other Form
Biophysics of RNA-Protein Interactions : A Mechanistic View
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Online Access
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Part 1: RNA Binding Proteins
Chapter 1: How proteins recognize RNA
Chapter 2: The interaction between L7Ae family of proteins and RNA kink turns
Chapter 3: Evolving methods in defining the role of RNA in RNP assembly
Chapter 4: Single-molecule studies of exonuclease: Following cleavage actions one step at a time
Chapter 5: Fitting in the age of single-molecule experiments: A guide to maximum-likelihood estimation and its advantages
Part II: Transcription and Translation
Chapter 6: A single-molecule view on cellular and viral RNA synthesis
Chapter 7: Single-Molecule Optical Tweezers Studies of Translation
Part III: RNA-Guided Protein Machineries
Chapter 8: Biophysical and biochemical approaches in the analysis of Argonaute-miRNA complexes
Chapter 9: Biophysics of RNA-guided CRISPR immunity
Chapter 10: Dynamics of MicroRNA Biogenesis.

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