Introduction: from mutations to new kinds of people
Genomic designation: how genetics creates new medical conditions
Immobile mutations: nowhere to go in the 1960s and 1970s (and the exception that proves the rule)
Leveraging mutations: going from the rare to the common in human genetics
The loops that tie: mutations in the trading zone of autism genetics
Assembling a new kind of person
Mutations in the clinic: reframing illness and redirecting medical practice
Remaking the normal versus the pathological in genetic medicine
The future for genomic designation and the new prenatal testing landscape
Conclusion.