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000917101 019__ $$a1129160475
000917101 020__ $$a9783030316686$$q(electronic book)
000917101 020__ $$a3030316688$$q(electronic book)
000917101 020__ $$z9783030316679
000917101 0247_ $$a10.1007/978-3-030-31668-6$$2doi
000917101 0247_ $$a10.1007/978-3-030-31
000917101 035__ $$aSP(OCoLC)on1127393622
000917101 035__ $$aSP(OCoLC)1127393622$$z(OCoLC)1129160475
000917101 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dLQU$$dUKMGB$$dOCLCF
000917101 049__ $$aISEA
000917101 050_4 $$aQR189$$b.R67 2019eb
000917101 08204 $$a615.3/72$$223
000917101 1001_ $$aRosales Mendoza, Sergio,$$eauthor.
000917101 24510 $$aNanovaccines :$$ban innovative technology to fight human and animal diseases /$$cSergio Rosales-Mendoza, Omar González-Ortega.
000917101 264_1 $$aCham :$$bSpringer,$$c[2019]
000917101 264_4 $$c©2019
000917101 300__ $$a1 online resource :$$billustrations.
000917101 336__ $$atext$$btxt$$2rdacontent
000917101 337__ $$acomputer$$bc$$2rdamedia
000917101 338__ $$aonline resource$$bcr$$2rdacarrier
000917101 504__ $$aIncludes bibliographical references and index.
000917101 5050_ $$aChapter 1. Nanovaccines and the history of vaccinology -- Chapter 2. The mucosal immune system an outlook for nanovaccines development -- Chapter 3. Gold-based mucosal nanovaccines -- Chapter 4. PLGA-based mucosal nanovaccines -- Chapter 5. Silica-based mucosal nanovaccines -- Chapter 6. Nanogels-based mucosal vaccines -- Chapter 7. Carbon nanotubes-based mucosal vaccines -- Chapter 8. Chitosan-based mucosal nanovaccines -- Chapter 9. Liposomes-based mucosal nanovaccines -- Chapter 10. Virus-like particles-based mucosal nanovaccines -- Chapter 11. Perspectives for field of nanovaccines.
000917101 506__ $$aAccess limited to authorized users.
000917101 520__ $$aThis book provides a compilation of the current developments in mucosal nanovaccines, which are an attractive approach to fight against infectious and non-communicable diseases. Since nanomaterials possess unique properties; many of them have a positive effect on vaccine efficacy when used as antigen carriers and have been applied in vaccinology with significant advances over the past years. This book addresses the methodologies for mucosal nanovaccines synthesis; based on the following nanomaterials: gold, PLGA, silica, and chitosan nanoparticles; as well as nanogels, carbon nanotubes, liposomes, and Virus-like particles. A description of the immunogenic properties of the mucosal nanovaccines is presented, highlighting the improvements achieved with this approach when compared to conventional formulations. Mucosal vaccines constitute the most practical immunization approach since they are easy to administer (promoting patient´s comfort and increasing compliance), allow triggering relevant immune responses at both the site of administration and distant compartments, and thus may protect the main entry portal for pathogens (oral, nasal, and genital mucosae). In this context, the potential of nanovaccines to result in new mucosal formulations in the benefit of global health is analyzed. Covers the synthesis and functionalization of nanomaterials for the development of nanovaccines; Discusses the underlying mechanisms involved in the induction of immune responses through mucosal compartments and the advantages of nanomaterials in the formulation of nanovaccines; Transmits the state of the art for the development of mucosal nanovaccines; Provides routes for the design and evaluation of mucosal nanovaccines; Presents key perspectives for the field of mucosal vaccine development.
000917101 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed November 13, 2019).
000917101 650_0 $$aVaccines.
000917101 650_0 $$aNanomedicine.
000917101 7001_ $$aGonzález-Ortega, Omar,$$eauthor.
000917101 852__ $$bebk
000917101 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-31668-6$$zOnline Access$$91397441.1
000917101 909CO $$ooai:library.usi.edu:917101$$pGLOBAL_SET
000917101 980__ $$aEBOOK
000917101 980__ $$aBIB
000917101 982__ $$aEbook
000917101 983__ $$aOnline
000917101 994__ $$a92$$bISE