000917447 000__ 03767cam\a2200409Ii\4500 000917447 001__ 917447 000917447 005__ 20230306150654.0 000917447 006__ m\\\\\o\\d\\\\\\\\ 000917447 007__ cr\nn\nnnunnun 000917447 008__ 191129s2019\\\\si\a\\\\o\\\\\000\0\eng\d 000917447 020__ $$a9789811506024$$q(electronic book) 000917447 020__ $$a9811506027$$q(electronic book) 000917447 020__ $$z9789811506017 000917447 0248_ $$a10.1007/978-981-15-0 000917447 035__ $$aSP(OCoLC)on1129165880 000917447 035__ $$aSP(OCoLC)1129165880 000917447 040__ $$aLQU$$beng$$cLQU$$dGW5XE 000917447 049__ $$aISEA 000917447 050_4 $$aQH581.2 000917447 08204 $$a611.01816 000917447 24500 $$aAutophagy :$$bbiology and diseases : basic science /$$cZheng-Hong Qin, editor. 000917447 264_1 $$aSingapore :$$bSpringer,$$c2019. 000917447 300__ $$a1 online resource (xv, 727 pages) :$$billustrations. 000917447 336__ $$atext$$btxt$$2rdacontent 000917447 337__ $$acomputer$$bc$$2rdamedia 000917447 338__ $$aonline resource$$bcr$$2rdacarrier 000917447 4901_ $$aAdvances in experimental medicine and biology ;$$vv. 1206 000917447 5050_ $$aHistory and current status of autophagy research -- Regulation of ATG and autophagy initiation -- Regulation of autophagy by mTOR signaling pathway -- AMPK and autophagy -- Beclin 1, Bcl-2 and autophagy -- TP53, TP53 target genes (DRAM, TIGAR) and autophagy -- Ca(2+) ion and autophagy -- Endoplasmic reticulum stress and autophagy -- Oxidative stress and autophagy -- Noncoding RNAs and atophagy -- Epigenetic regulation of autophagy -- Protein modification and autophagy activation -- Other molecular mechanisms regulating Autophagy -- The role of nanomaterials in autophagy -- Structural basis of autophagy regulatory proteins -- Autophagy and energy metabolism -- Autophagy and lipid metabolism -- Autophagy and the metabolism of misfolding protein -- Autophagy in mitochondrial quality control -- Chaperone-mediated autophagy -- Autophagy in reproduction -- Autophagy in development and differentiation -- Autophagy in normal stem cells and specialized cells -- Autophagy, aging and longevity -- Autophagy and the ubiquitin-proteasome system -- Immuno-signal and autophagy regulation -- Autophagy and the immune response -- Autophagy and immune tolerance -- Autophagy and cell survival and death -- Coordination of autophagy and other cellular activities. 000917447 506__ $$aAccess limited to authorized users. 000917447 520__ $$aThis book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy. 000917447 650_0 $$aCytology. 000917447 7001_ $$aQin, Zheng-Hong. 000917447 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1206. 000917447 852__ $$bebk 000917447 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-15-0602-4$$zOnline Access$$91397441.1 000917447 909CO $$ooai:library.usi.edu:917447$$pGLOBAL_SET 000917447 980__ $$aEBOOK 000917447 980__ $$aBIB 000917447 982__ $$aEbook 000917447 983__ $$aOnline 000917447 994__ $$a92$$bISE