@article{922566,
      recid = {922566},
      author = {Khurana, Sandhya, and Holguin, Fernando,},
      title = {Difficult to treat asthma : clinical essentials /},
      pages = {1 online resource :},
      note = {Includes index.},
      abstract = {This book provides a practical, stepwise, evidence-based  approach to effective management of patients with difficult  to treat asthma. The impact of asthma on morbidity and  healthcare utilization increases exponentially with  severity. Severe refractory asthma accounts for less than  5% of all asthma. Its prevalence, however, is often  overestimated as there are several other confounding  factors that make asthma 'difficult to treat'. Many novel  (albeit expensive) therapies are now available and  providers caring for patients with severe asthma are  charged with selecting the best evidence treatment. This  calls for complex and nuanced decision-making. Whether  people with asthma gain and maintain control over their  condition depends not only on the availability of effective  drugs, but also multiple patient and healthcare provider  behaviors. Therefore, now more than ever, it has become  increasingly important to differentiate "difficult" from  "severe refractory" asthma to allow identification of  patients most likely to benefit from these therapies. This  volume delves into the current understanding of mechanisms  and increasingly recognized heterogeneity of this complex  disease. It discusses a structured approach to  identification and optimization of factors contributing to  poor asthma control, including nonadherence, comorbidities  and occupational/environmental triggers. The book includes  'state of the art' reviews on recent advances in  traditional and targeted asthma therapies, as well as a  glimpse into what the future may hold. Highlights include a  comprehensive guide to management of severe asthma in  children and pregnancy, as well as practical considerations  to management of asthma based on different clinical  phenotypes. Each chapter is authored by leading experts in  the field who share their own clinical approach. This is an  ideal guide for clinical pulmonologists and  allergist/immunologists, as well as primary care providers,  physician extenders in specialty practice, physicians in  pulmonary/allergy training, and even industry partners. },
      url = {http://library.usi.edu/record/922566},
      doi = {https://doi.org/10.1007/978-3-030-20812-7},
}