000922566 000__ 04582cam\a2200469Ii\4500 000922566 001__ 922566 000922566 005__ 20230306150842.0 000922566 006__ m\\\\\o\\d\\\\\\\\ 000922566 007__ cr\cn\nnnunnun 000922566 008__ 190913s2020\\\\sz\a\\\\o\\\\\001\0\eng\d 000922566 019__ $$a1121099324 000922566 020__ $$a9783030208127$$q(electronic book) 000922566 020__ $$a3030208125$$q(electronic book) 000922566 020__ $$z9783030208110 000922566 0247_ $$a10.1007/978-3-030-20812-7$$2doi 000922566 035__ $$aSP(OCoLC)on1119538284 000922566 035__ $$aSP(OCoLC)1119538284$$z(OCoLC)1121099324 000922566 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dUKMGB$$dOCLCF$$dSFB 000922566 049__ $$aISEA 000922566 050_4 $$aRC591$$b.D54 2020eb 000922566 08204 $$a616.2/3806$$223 000922566 24500 $$aDifficult to treat asthma :$$bclinical essentials /$$cSandhya Khurana, Fernando Holguin, editors. 000922566 264_1 $$aCham :$$bHumana Press,$$c[2020] 000922566 264_4 $$c©2020 000922566 300__ $$a1 online resource :$$billustrations. 000922566 336__ $$atext$$btxt$$2rdacontent 000922566 337__ $$acomputer$$bc$$2rdamedia 000922566 338__ $$aonline resource$$bcr$$2rdacarrier 000922566 4901_ $$aRespiratory medicine,$$x2197-7372 000922566 500__ $$aIncludes index. 000922566 5050_ $$aScope of the problem, definition and pathophysiology -- Is it Asthma? Recognizing asthma mimics -- Beyond Refills: Promoting Adherence to Optimize Outcomes -- Addressing Comorbidities in Difficult Asthma -- Evaluation and Management of Work-Related Asthma -- Advances in Inhaled Medications -- Heterogeneity in Severe asthma -- Biomarkers, Targeted Therapies, Biologics and Bronchial Thermoplasty -- Practical Considerations in Management of Allergic Asthma -- Practical considerations in the management of eosinophilic asthma -- Practical considerations in management of non-eosinophilic asthma -- Practical considerations in management of obesity associated asthma -- Severe asthma in pregnancy: Special considerations -- Severe asthma in childhood: Special considerations -- High-risk asthma clinic: Putting it all together -- Difficult Asthma: Unmet Needs and Future Directions. 000922566 506__ $$aAccess limited to authorized users. 000922566 520__ $$aThis book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. The impact of asthma on morbidity and healthcare utilization increases exponentially with severity. Severe refractory asthma accounts for less than 5% of all asthma. Its prevalence, however, is often overestimated as there are several other confounding factors that make asthma 'difficult to treat'. Many novel (albeit expensive) therapies are now available and providers caring for patients with severe asthma are charged with selecting the best evidence treatment. This calls for complex and nuanced decision-making. Whether people with asthma gain and maintain control over their condition depends not only on the availability of effective drugs, but also multiple patient and healthcare provider behaviors. Therefore, now more than ever, it has become increasingly important to differentiate "difficult" from "severe refractory" asthma to allow identification of patients most likely to benefit from these therapies. This volume delves into the current understanding of mechanisms and increasingly recognized heterogeneity of this complex disease. It discusses a structured approach to identification and optimization of factors contributing to poor asthma control, including nonadherence, comorbidities and occupational/environmental triggers. The book includes 'state of the art' reviews on recent advances in traditional and targeted asthma therapies, as well as a glimpse into what the future may hold. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes. Each chapter is authored by leading experts in the field who share their own clinical approach. This is an ideal guide for clinical pulmonologists and allergist/immunologists, as well as primary care providers, physician extenders in specialty practice, physicians in pulmonary/allergy training, and even industry partners. 000922566 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 13, 2019). 000922566 650_0 $$aAsthma$$xTreatment. 000922566 7001_ $$aKhurana, Sandhya,$$eeditor. 000922566 7001_ $$aHolguin, Fernando,$$eeditor. 000922566 830_0 $$aRespiratory medicine (New York, N.Y.) 000922566 852__ $$bebk 000922566 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-20812-7$$zOnline Access$$91397441.1 000922566 909CO $$ooai:library.usi.edu:922566$$pGLOBAL_SET 000922566 980__ $$aEBOOK 000922566 980__ $$aBIB 000922566 982__ $$aEbook 000922566 983__ $$aOnline 000922566 994__ $$a92$$bISE