000922984 000__ 03560cam\a2200469Ii\4500 000922984 001__ 922984 000922984 005__ 20230306150908.0 000922984 006__ m\\\\\o\\d\\\\\\\\ 000922984 007__ cr\cn\nnnunnun 000922984 008__ 191016s2020\\\\sz\\\\\\o\\\\\000\0\eng\d 000922984 020__ $$a9783030264390$$q(electronic book) 000922984 020__ $$a3030264394$$q(electronic book) 000922984 020__ $$z9783030264383 000922984 0247_ $$a10.1007/978-3-030-26439-0$$2doi 000922984 035__ $$aSP(OCoLC)on1123194002 000922984 035__ $$aSP(OCoLC)1123194002 000922984 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dOCLCF$$dUKMGB$$dOKS 000922984 049__ $$aISEA 000922984 050_4 $$aRC255 000922984 08204 $$a616.99/4075$$223 000922984 24500 $$aTumor liquid biopsies /$$cedited by Florence Schaffner, Jean-Louis Merlin, Nikolas von Bubnoff. 000922984 264_1 $$aCham, Switzerland :$$bSpringer,$$c2020. 000922984 300__ $$a1 online resource (vi, 368 pages). 000922984 336__ $$atext$$btxt$$2rdacontent 000922984 337__ $$acomputer$$bc$$2rdamedia 000922984 338__ $$aonline resource$$bcr$$2rdacarrier 000922984 4901_ $$aRecent results in cancer research,$$x0080-0015 ;$$vvolume 215 000922984 5050_ $$aCirculating Tumor Cells: Pathophysiology of Tumor Cell Release into the Circulation and characterization of CTC -- CTC enrichment technologies -- Genotyping of CTC :example Lung cancer -- CTC in Breast Cancer: a clinical approach -- Circulating Tumor DNA: Pathophysiology of ctDNA Release into the Circulation and its characterization -- Enrichment and Analysis of ctDNA -- ctDNA in Lung Cancer -- ctDNA in Breast Cancer -- ctDNA in Colorectal Cancer -- Dynamic Treatment Stratification using ctDNA -- Circulating Tumor RNA: Noncoding Tumor RNAs: Pathophysiology of Release and Techniques of Detection -- Circulating miRNAs as Biomarker in Cancer -- Plasma Subcompartments as Source for Tumor derived Biomarkers: Exosomes and Vesicles as Biomarker in Cancer -- Quantitative proteomic Analysis of Plasma in Cancer. 000922984 506__ $$aAccess limited to authorized users. 000922984 520__ $$aThis book is a comprehensive guide to the techniques, clinical applications, and benefits of the different forms of liquid biopsy employed in patients with a variety of tumor types, including lung, breast and colorectal cancer. Offering detailed explanations, it discusses the how changes in tumors can be tracked using these cutting-edge technologies, which enable the detection and analysis of diverse circulating biomarkers: tumor cells, tumor DNA, tumor RNA (free or in exosomes), and fluid biomarkers identifiable by means of targeted proteomics. The use of such advanced technologies is enabling us to tackle questions and problems in a way that was not possible just a few years ago. We now have at our disposal an effective means of overcoming the problem of intratumor heterogeneity, which has limited the value of conventional biopsy approaches. As a consequence, oncology practice is about to change radically, toward truly personalized precision medicine. This book provides both clinicians and researchers with a thorough and up-to-date overview of progress in the field. 000922984 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 16, 2019). 000922984 650_0 $$aTumors$$xDiagnosis. 000922984 650_0 $$aCancer$$xDiagnosis. 000922984 650_0 $$aBiopsy. 000922984 7001_ $$aSchaffner, Florence,$$eeditor. 000922984 7001_ $$aMerlin, Jean-Louis,$$eeditor. 000922984 7001_ $$aBubnoff, Nikolas von,$$eeditor. 000922984 830_0 $$aRecent results in cancer research ;$$v215. 000922984 852__ $$bebk 000922984 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-26439-0$$zOnline Access$$91397441.1 000922984 909CO $$ooai:library.usi.edu:922984$$pGLOBAL_SET 000922984 980__ $$aEBOOK 000922984 980__ $$aBIB 000922984 982__ $$aEbook 000922984 983__ $$aOnline 000922984 994__ $$a92$$bISE