000923158 000__ 06003cam\a2200517Ii\4500 000923158 001__ 923158 000923158 005__ 20230306151011.0 000923158 006__ m\\\\\o\\d\\\\\\\\ 000923158 007__ cr\un\nnnunnun 000923158 008__ 191031s2020\\\\sz\a\\\\o\\\\\001\0\eng\d 000923158 019__ $$a1129298625 000923158 020__ $$a9783030124571$$q(electronic book) 000923158 020__ $$a3030124576$$q(electronic book) 000923158 020__ $$z9783030124564 000923158 020__ $$z3030124568 000923158 0247_ $$a10.1007/978-3-030-12457-1$$2doi 000923158 035__ $$aSP(OCoLC)on1125946762 000923158 035__ $$aSP(OCoLC)1125946762$$z(OCoLC)1129298625 000923158 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dUKMGB$$dUPM$$dOCLCF$$dN$T$$dMMU$$dOCLCO 000923158 049__ $$aISEA 000923158 050_4 $$aQP535.C2 000923158 08204 $$a572/.516$$223 000923158 24500 $$aCalcium signaling /$$cMd. Shahidul Islam, editor. 000923158 250__ $$aSecond edition. 000923158 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2020]. 000923158 264_4 $$c©2020 000923158 300__ $$a1 online resource (xiii, 1110 pages) :$$billustrations. 000923158 336__ $$atext$$btxt$$2rdacontent 000923158 337__ $$acomputer$$bc$$2rdamedia 000923158 338__ $$aonline resource$$bcr$$2rdacarrier 000923158 347__ $$atext file$$bPDF$$2rda 000923158 4901_ $$aAdvances in experimental medicine and biology,$$x0065-2598 ;$$vvolume 1131 000923158 504__ $$aIncludes bibliographical references and index. 000923158 5050_ $$aCalcium signaling: from basic to bedside -- Measuring Ca2+ in living cells -- High-throughput fluorescence assays for ion channels and GPCRs -- Imaging native calcium currents in brain slices -- Molecular diversity of plasma membrane Ca2+ transporting ATPases: their function under normal and pathological conditions -- A role for SERCA pumps in the neurobiology of neuropsychiatric and neurodegenerative disorders -- Cytoplasmic calcium buffering: an integrative crosstalk -- An update to calcium binding proteins -- Phospholipase C -- New insights in the IP3 receptor and its regulation -- Expression of the inositol 1,4,5-trisphosphate receptor and the ryanodine receptor Ca2+-release channels in the beta-cells and alpha-cells of the human islets of langerhans -- Evolution of excitation-contraction coupling -- Molecular insights into calcium dependent regulation of ryanodine receptor calcium release channels -- Sarco-endoplasmic reticulum calcium release model based on changes in the luminal calcium content -- Pyridine nucleotide metabolites and calcium release from intracellular stores -- Calcium signaling in the heart -- Molecular basis and regulation of store-operated calcium entry -- Canonical transient potential receptor-3 channels in normal and diseased airway smooth muscle cells -- Pathophysiological significance of store-operated calcium entry in cardiovascular and skeletal muscle disorders and angiogenesis -- Calcium signaling and the regulation of chemosensitivity in cancer cells: role of the transient receptor potential channels -- Widespread roles of CaMK-II in developmental pathways -- Calcium signaling and gene expression -- Review: structure and activation mechanisms of CRAC channels -- Targeting transient receptor potential channels by microRNAs drives tumor development and progression -- Calcium channels and calcium-regulated channels in human red blood cells -- Regulation of multifunctional calcium/calmodulin stimulated protein kinases by molecular targeting -- Readily releasable stores of calcium in neuronal endolysosomes: physiological and pathophysiological relevance -- At the crossing of ER Stress and MAMs: a key role of sigma-1 receptor? -- Er-mitochondria calcium transfer, organelle contacts and neurodegenerative diseases -- The role of mitochondrial calcium signaling in the pathophysiology of cancer cells -- Simulation strategies for calcium microdomains and calcium noise -- A statistical view on calcium oscillations -- Calcium regulation of bacterial virulence -- Ca2+ signaling in drosophila photoreceptor cells -- Calcium imaging in drosophila melanogaster -- Calcium imaging in the zebrafish -- Stimulus-secretion coupling in beta-cells: from basic to bedside -- Calcium dynamics and synaptic plasticity -- Calcium signaling during brain aging and its influence on the hippocampal synaptic plasticity -- Calcium signaling in endothelial colony forming cells in health and disease -- Sensing extracellular calcium: an insight into the structure and function of the calcium-sensing receptor (CaSR) -- Extracellular Ca2+ in bone marrow -- Calcium in cell-extracellular matrix interactions. 000923158 506__ $$aAccess limited to authorized users. 000923158 520__ $$a"This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish"--Publisher's description. 000923158 588__ $$aDescription based on online resource; title from resource home page (viewed January 21, 2020). 000923158 650_0 $$aCalcium ions. 000923158 650_0 $$aCellular signal transduction. 000923158 7001_ $$aIslam, Md. Shahidul,$$d1956-$$eeditor. 000923158 77608 $$iPrint version:$$tCalcium signaling.$$bSecond edition.$$dCham, Switzerland : Springer, [2020]$$z9783030124564$$w(OCoLC)1080429879 000923158 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1131. 000923158 852__ $$bebk 000923158 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-12457-1$$zOnline Access$$91397441.1 000923158 909CO $$ooai:library.usi.edu:923158$$pGLOBAL_SET 000923158 980__ $$aEBOOK 000923158 980__ $$aBIB 000923158 982__ $$aEbook 000923158 983__ $$aOnline 000923158 994__ $$a92$$bISE