000923437 000__ 03152cam\a2200409Ii\4500 000923437 001__ 923437 000923437 005__ 20230306151027.0 000923437 006__ m\\\\\o\\d\\\\\\\\ 000923437 007__ cr\cn\nnnunnun 000923437 008__ 191119s2020\\\\sz\\\\\\o\\\\\001\0\eng\d 000923437 020__ $$a9783030273590$$q(electronic book) 000923437 020__ $$a3030273598$$q(electronic book) 000923437 020__ $$z9783030273583 000923437 0247_ $$a10.1007/978-3-030-27359-0$$2doi 000923437 035__ $$aSP(OCoLC)on1128024292 000923437 035__ $$aSP(OCoLC)1128024292 000923437 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dUKMGB$$dN$T$$dOCLCF 000923437 049__ $$aISEA 000923437 050_4 $$aRC280.B7 000923437 08204 $$a616.99481$$223 000923437 24500 $$aGlioma imaging :$$bphysiologic, metabolic, and molecular approaches /$$cWhitney B. Pope, editor. 000923437 264_1 $$aCham :$$bSpringer,$$c2020. 000923437 300__ $$a1 online resource (xiv, 286 pages) :$$billustrations. 000923437 336__ $$atext$$btxt$$2rdacontent 000923437 337__ $$acomputer$$bc$$2rdamedia 000923437 338__ $$aonline resource$$bcr$$2rdacarrier 000923437 500__ $$aIncludes index. 000923437 506__ $$aAccess limited to authorized users. 000923437 520__ $$aThis book covers physiologic, metabolic and molecular imaging for gliomas. Gliomas are the most common primary brain tumors. Imaging is critical for glioma management because of its ability to noninvasively define the anatomic location and extent of disease. While conventional MRI is used to guide current treatments, multiple studies suggest molecular features of gliomas may be identified with noninvasive imaging, including physiologic MRI and amino acid positron emission tomography (PET). These advanced imaging techniques have the promise to help elucidate underlying tumor biology and provide important information that could be integrated into routine clinical practice. The text outlines current clinical practice including common scenarios in which imaging interpretation impacts patient management. Gaps in knowledge and potential areas of advancement based on the application of more experimental imaging techniques will be discussed. In reviewing this book, readers will learn: current standard imaging methodologies used in clinical practice for patients undergoing treatment for glioma and the implications of emerging treatment modalities including immunotherapy the theoretical basis for advanced imaging techniques including diffusion and perfusion MRI, MR spectroscopy, CEST and amino acid PET the relationship between imaging and molecular/genomic glioma features incorporated in the WHO 2016 classification update and the potential application of machine learning about the recently adopted and FDA approved standard brain tumor protocol for multicenter drug trials of the gaps in knowledge that impede optimal patient management and the cutting edge imaging techniques that could address these deficits. 000923437 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed November 18, 2019). 000923437 650_0 $$aGliomas$$xImaging. 000923437 650_0 $$aBrain$$xTumors. 000923437 7001_ $$aPope, Whitney B.$$eeditor. 000923437 852__ $$bebk 000923437 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-27359-0$$zOnline Access$$91397441.1 000923437 909CO $$ooai:library.usi.edu:923437$$pGLOBAL_SET 000923437 980__ $$aEBOOK 000923437 980__ $$aBIB 000923437 982__ $$aEbook 000923437 983__ $$aOnline 000923437 994__ $$a92$$bISE