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Part I: Achieving Stereotactic Precision
Traditional and Mini-Frames
Stereotactic Robots
Intraoperative Magnetic Resonance Imaging and Computed Tomoraphy
Frameless Image Guidance in Stereotactic Radiosurgery
Part II: Defining Trajectories and Targets
Principles of Safe Sterotactic Trajectories
Structural Imaging and Target Visualization
Network-Based Imaging and Connections
Microelectrode Recording in Neurosurgical Patients
Local Field Potentials and ECoG
Awake Testing to Confirm Target Engagement
Cloud-Based Stereotactic and Functional Neurosurgery and Registries
Part III: The Biophysics of Stereotactic Therapy
Responsive Neurostimulation
Spinal Stimulation
Peripheral Nerve Stimulation
Non-Invasive Central Neuromodulation with Transcranial Magnetic Stimulation
Ablation: Radiofrequency, Laser, and HIFU
Radiosurgery
Part IV: Diseases and Targets
Parkinson's Disease: Deep Brain Stimulation
Parkinson's Disease: Lesions
Deep Brain Stimulation and Essential Tremor
Essential Tremor: Lesions
Dystonia
Invasive Monitoring in Epilepsy Surgery
Epilepsy: Mesial Temporal
Neocortical Epilespy
Stereotactic Neurosurgery for the Management and Treatment of Pediatric Epilepsy
Epilepsy: Neuromodulation
Deep Brain Stimulation for Treatment-Resistant Depression
Deep Brain Stimulation for Obsessive Compulsive Disorder
Stereotactic Lesion Procedures for Obsessive-Compulsive Disorder
Deep Brain Stimulation for Gilles de la Tourette Syndrome
Neuromodulation for Chronic Pain
Chronic Pain: Lesion
Deep Brain Stimulation for Cluster Headache
Part V: The Future of Functional Neurosurgery
Developing New Indications: Strategies and Hurdles to Discovery
Imaging: Patient Selection, Targeting, and Outcome Biomarkers
The Design of Clinical Studies for Neuromodulation
Registries and Big Data.

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