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Thyroid and heart : a comprehensive translational essay / Giorgio Iervasi, Alessandro Pingitore, A. Martin Gerdes, Salman Razvi, editors.

2nd ed.

9783030368715 (electronic book)
3030368718 (electronic book)
9783030368708

Cham : Springer, 2020.

English

1 online resource (429 pages)

10.1007/978-3-030-36871-5 doi

RC682

616.1/2

In recent years, several scientific papers have highlighted the role of the thyroid system in cardioprotection, and several clinical studies - including multicenter studies - have identified the role of thyroid hormones (TH) in the development and progression of cardiovascular disease, making an update of TH and heart relationship both necessary and timely. This second edition of Thyroid and Heart failure provides a careful and updated review of the experimental, clinical and epidemiological results in the field of TH and heart failure, with a particular focus on the translational - bench to bedside - significance of the obtained results. It discusses topics such as the molecular, structural, functional, cellular and histological cardiac changes; the reversibility of these changes with TH replacement therapy; the systemic effects - kidney, hormonal pathways systems, brain, muscle, etc - of altered TH metabolism in HF, as well as the clinical and prognostic implications. The section devoted to the potential therapeutic treatments has been expanded. Thanks to its translational approach to this highly complex subject, the book will be of interest to a broad readership, including cardiologists, endocrinologists and internists.

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