000931386 000__ 03952cam\a2200445Ia\4500 000931386 001__ 931386 000931386 005__ 20230306151510.0 000931386 006__ m\\\\\o\\d\\\\\\\\ 000931386 007__ cr\un\nnnunnun 000931386 008__ 200411s2020\\\\si\\\\\\o\\\\\000\0\eng\d 000931386 019__ $$a1152540066$$a1153164309$$a1153954011 000931386 020__ $$a9789811525179$$q(electronic book) 000931386 020__ $$a981152517X$$q(electronic book) 000931386 020__ $$z9811525161 000931386 020__ $$z9789811525162 000931386 0248_ $$a10.1007/978-981-15-2 000931386 035__ $$aSP(OCoLC)on1149279131 000931386 035__ $$aSP(OCoLC)1149279131$$z(OCoLC)1152540066$$z(OCoLC)1153164309$$z(OCoLC)1153954011 000931386 040__ $$aYDX$$beng$$epn$$cYDX$$dGW5XE$$dLQU$$dOCLCQ 000931386 049__ $$aISEA 000931386 050_4 $$aRC685.C6 000931386 08204 $$a616.1/2306$$223 000931386 24500 $$aCoronary artery disease :$$btherapeutics and drug discovery /$$cMiao Wang, editor. 000931386 260__ $$aSingapore :$$bSpringer,$$c2020. 000931386 300__ $$a1 online resource 000931386 336__ $$atext$$btxt$$2rdacontent 000931386 337__ $$acomputer$$bc$$2rdamedia 000931386 338__ $$aonline resource$$bcr$$2rdacarrier 000931386 4901_ $$aAdvances in Experimental Medicine and Biology,$$x0065-2598 ;$$vv. 1177 000931386 5050_ $$aCoronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease. 000931386 506__ $$aAccess limited to authorized users. 000931386 520__ $$aThis book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders. 000931386 650_0 $$aCoronary heart disease$$xTreatment. 000931386 7001_ $$aWang, Miao. 000931386 77608 $$iPrint version:$$tCoronary artery disease.$$dSingapore : Springer, 2020$$z9811525161$$z9789811525162$$w(OCoLC)1130272797 000931386 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1177. 000931386 852__ $$bebk 000931386 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-15-2517-9$$zOnline Access$$91397441.1 000931386 909CO $$ooai:library.usi.edu:931386$$pGLOBAL_SET 000931386 980__ $$aEBOOK 000931386 980__ $$aBIB 000931386 982__ $$aEbook 000931386 983__ $$aOnline 000931386 994__ $$a92$$bISE