000931810 000__ 02864cam\a2200457Ii\4500 000931810 001__ 931810 000931810 005__ 20230306151704.0 000931810 006__ m\\\\\o\\d\\\\\\\\ 000931810 007__ cr\nn\nnnunnun 000931810 008__ 200428s2020\\\\si\\\\\\o\\\\\000\0\eng\d 000931810 019__ $$a1152995690$$a1153075996$$a1153959653$$a1154487256 000931810 020__ $$a9789811535321$$q(electronic book) 000931810 020__ $$a9811535329$$q(electronic book) 000931810 020__ $$z9789811535314 000931810 020__ $$z9811535310 000931810 0248_ $$a10.1007/978-981-15-3 000931810 035__ $$aSP(OCoLC)on1152540648 000931810 035__ $$aSP(OCoLC)1152540648$$z(OCoLC)1152995690$$z(OCoLC)1153075996$$z(OCoLC)1153959653$$z(OCoLC)1154487256 000931810 040__ $$aLQU$$beng$$cLQU$$dGW5XE$$dYDX$$dEBLCP 000931810 049__ $$aISEA 000931810 050_4 $$aQR185.8.B15 000931810 08204 $$a616.079/8$$223 000931810 08204 $$a616.079 000931810 24500 $$aB cells in immunity and tolerance /$$cedited by Ji-Yang Wang. 000931810 264_1 $$aSingapore :$$bSpringer,$$c2020. 000931810 300__ $$a1 online resource (xii, 181 pages) :$$billustrations. 000931810 336__ $$atext$$btxt$$2rdacontent 000931810 337__ $$acomputer$$bc$$2rdamedia 000931810 338__ $$aonline resource$$bcr$$2rdacarrier 000931810 4901_ $$aAdvances in experimental medicine and biology ;$$vv. 1254 000931810 5050_ $$aB cell development and maturation -- B cell receptor signalling -- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger -- Germinal center reaction -- Memory B cells in local and systemic sites -- Regulation of plasma cell differentiation -- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor -- Regulatory B cells -- Diversified IgA-bacteria interaction in gut homeostasis -- Primary antibody deficiencies -- B cell-mediated autoimmune diseases -- B cell lymphomas. 000931810 506__ $$aAccess limited to authorized users. 000931810 520__ $$aThis book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians. 000931810 650_0 $$aB cells. 000931810 7001_ $$aWang, Ji-Yang. 000931810 77608 $$iPrint version: $$z9811535310$$z9789811535314$$w(OCoLC)1138548300 000931810 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1254. 000931810 852__ $$bebk 000931810 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-15-3532-1$$zOnline Access$$91397441.1 000931810 909CO $$ooai:library.usi.edu:931810$$pGLOBAL_SET 000931810 980__ $$aEBOOK 000931810 980__ $$aBIB 000931810 982__ $$aEbook 000931810 983__ $$aOnline 000931810 994__ $$a92$$bISE