Acute kidney injury and regenerative medicine / Yoshio Terada, Takashi Wada, Kent Doi, editors.
Terada, Yoshio.; Wada, Takashi.; Doi, Kent.
2020
RC918.R4
Available Online

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Title Acute kidney injury and regenerative medicine / Yoshio Terada, Takashi Wada, Kent Doi, editors.
ISBN 9789811511080 (electronic book)
981151108X (electronic book)
9811511071
9789811511073
DOI https://doi.org/10.1007/978-981-15-1
https://doi.org/10.1007/978-981-15-1108-0
Imprint Singapore : Springer, 2020.
Language English
Description 1 online resource
Other Standard Identifiers 10.1007/978-981-15-1
10.1007/978-981-15-1108-0 doi
Call Number RC918.R4
Dewey Decimal Classification 616.6/1
Summary This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis. Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.
Access Note Access limited to authorized users.
Digital File Characteristics text file PDF
Added Author Terada, Yoshio.
Wada, Takashi.
Doi, Kent.
Available in Other Form Print version: 9789811511073
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Part 1 Diagnosis and risk factors of AKI
Definition and epidemiology of AKI
Cause of AKI (prerenal, renal, postrenal)
Pathophysiology of AKI
Diagnosis of AKI (clinical assessment, novel biomarkers)
Risk factors for AKI development in surgery
Risk factors for AKI development in heart failure
7. Contrast-induced AKI
8. Antibiotics- and immunosuppression-related AKI
9. AKI in setting of cancer
Community-acquired AKI and hospital-acquired AKI
Part 2 Complication of AKI
11. Complication of homeostasis (mineral and acid-base)
12. Volume overload and cardiac and pulmonary complication
Part 3 Prevention and management of AKI
Prerenal and renal AKI
Postrenal AKI
AKI in intensive care medicine
Nondialytic supportive management of AKI
Renal replacement therapy in AKI
Outcomes and long-term follow-up of AKI patients
Prevention and management of pediatric AKI
Part 4 Experimental novel findings
AKI-to-CKD transition
AKI and nerve system
AKI and immune system
AKI and cytokines
Part 5 AKI and regenerative medicine
iPS cell and renal regenerative medicine
Embryonic genes and renal regenerative medicine
Xenotransplanted embryonic kidney.

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