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Table of Contents
Part 1 Introduction
1 History of research
Part 2 Epidemiology
2 An Overview of Epidemiology and Genetics
3 OPLL: Disease entity, prevalence, literature research, and growth
4 Natural History of Ossification of the Posterior Longitudinal Ligament (OPLL)
Part 3 Pathology & Pathogenesis
5 Overview of Recent Basic Researches on OPLL and OLF
6 Histopathological Features of Ossification of the Posterior Longitudinal Ligament
7 Ectopic Ossification of Human Spinal Ligaments Caused by Mesenchymal Stem Cell Abnormalities
8 A Short History of Genetic Study of OPLL
9 Overview of possible roles of OPLL-associated genes in OPLL development
10 Application of iPS cell technology for OPLL
11 Mechanisms underlying OPLL development in Tiptoe Walking (ttw) Mice
12 In vivo tracing of neural tracts in tip-toe walking Yoshimura mice by diffusion tensor tractography
13 Metabolomics analysis in OPLL patients
Part 4 Diagnosis
14 Diagnosis of OPLL and OLF: overview
15 Clinical manifestation of cervical OPLL
16 Three-dimensional imaging of cervical ossification of the posterior longitudinal ligament
17 Clinical manifestations of thoracic ossification of the posterior longitudinal ligament (OPLL) and ossification of the ligament flavum (OLF)
18 Evaluation of distribution patterns of spinal ligament ossification using whole-spine computed tomography in patients with cervical ossification of the posterior longitudinal ligament
19 Diagnostic imaging of thoracic OPLL and OLF
20 Biomechanics of the spinal cord compression due to cervical ossification of the posterior longitudinal ligament
Part 5 Treatment
21 Surgical Indications and Choice of Surgical Procedure for Cervical Ossification of the Longitudinal Ligament
22 Overview of Laminoplasty
23 Open-door Laminoplasty for Cervical OPLL: Technique, Long-term Results, and Complications
24 Double-door Laminoplasty for Cervical OPLL : Technique, Complications and Long-term Results
25 Posterior Decompression and Fusion for Cervical OPLL: Indication and Technique
26 Anterior Cervical Decompression for Cervical OPLL: Technique, Complications and Long-term Results
27 Surgical Indications and Choice of Surgical Procedure for Thoracic OPLL
28 Posterior decompression and fusion for thoracic OPLL: surgical techniques, outcomes, timing and complications
29 Anterior Decompression and Fusion for Thoracic OPLL: Transthoracic and Transsternal Approaches
30 Circumferential Decompression Through Posterior Approach for Thoracic OPLL: Technique and Complications
31 Surgery for ossification of the ligamentum flavum: posterior decompression with or without fusion
32 Computer-Aided Surgery for Ossification of the Spinal Ligaments
33 Surgical Treatment of Thoracic Ossification of the Posterior Longitudinal Ligament: Intraoperative Spinal Cord Monitoring
34 Intraoperative ultrasonography for patients with ossification of the posterior longitudinal ligament.
1 History of research
Part 2 Epidemiology
2 An Overview of Epidemiology and Genetics
3 OPLL: Disease entity, prevalence, literature research, and growth
4 Natural History of Ossification of the Posterior Longitudinal Ligament (OPLL)
Part 3 Pathology & Pathogenesis
5 Overview of Recent Basic Researches on OPLL and OLF
6 Histopathological Features of Ossification of the Posterior Longitudinal Ligament
7 Ectopic Ossification of Human Spinal Ligaments Caused by Mesenchymal Stem Cell Abnormalities
8 A Short History of Genetic Study of OPLL
9 Overview of possible roles of OPLL-associated genes in OPLL development
10 Application of iPS cell technology for OPLL
11 Mechanisms underlying OPLL development in Tiptoe Walking (ttw) Mice
12 In vivo tracing of neural tracts in tip-toe walking Yoshimura mice by diffusion tensor tractography
13 Metabolomics analysis in OPLL patients
Part 4 Diagnosis
14 Diagnosis of OPLL and OLF: overview
15 Clinical manifestation of cervical OPLL
16 Three-dimensional imaging of cervical ossification of the posterior longitudinal ligament
17 Clinical manifestations of thoracic ossification of the posterior longitudinal ligament (OPLL) and ossification of the ligament flavum (OLF)
18 Evaluation of distribution patterns of spinal ligament ossification using whole-spine computed tomography in patients with cervical ossification of the posterior longitudinal ligament
19 Diagnostic imaging of thoracic OPLL and OLF
20 Biomechanics of the spinal cord compression due to cervical ossification of the posterior longitudinal ligament
Part 5 Treatment
21 Surgical Indications and Choice of Surgical Procedure for Cervical Ossification of the Longitudinal Ligament
22 Overview of Laminoplasty
23 Open-door Laminoplasty for Cervical OPLL: Technique, Long-term Results, and Complications
24 Double-door Laminoplasty for Cervical OPLL : Technique, Complications and Long-term Results
25 Posterior Decompression and Fusion for Cervical OPLL: Indication and Technique
26 Anterior Cervical Decompression for Cervical OPLL: Technique, Complications and Long-term Results
27 Surgical Indications and Choice of Surgical Procedure for Thoracic OPLL
28 Posterior decompression and fusion for thoracic OPLL: surgical techniques, outcomes, timing and complications
29 Anterior Decompression and Fusion for Thoracic OPLL: Transthoracic and Transsternal Approaches
30 Circumferential Decompression Through Posterior Approach for Thoracic OPLL: Technique and Complications
31 Surgery for ossification of the ligamentum flavum: posterior decompression with or without fusion
32 Computer-Aided Surgery for Ossification of the Spinal Ligaments
33 Surgical Treatment of Thoracic Ossification of the Posterior Longitudinal Ligament: Intraoperative Spinal Cord Monitoring
34 Intraoperative ultrasonography for patients with ossification of the posterior longitudinal ligament.