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000933083 019__ $$a1155720431$$a1155883538$$a1156424006$$a1156744236
000933083 020__ $$a9783030445997$$q(electronic book)
000933083 020__ $$a3030445992$$q(electronic book)
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000933083 020__ $$z9783030445973
000933083 0248_ $$a10.1007/978-3-030-44
000933083 035__ $$aSP(OCoLC)on1156110460
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000933083 08204 $$a572.8/845$$223
000933083 08204 $$a616.079
000933083 24500 $$aNrf2 and its modulation in inflammation /$$cHuai Deng, editor.
000933083 260__ $$aCham :$$bSpringer,$$c2020.
000933083 300__ $$a1 online resource (210 pages).
000933083 336__ $$atext$$btxt$$2rdacontent
000933083 337__ $$acomputer$$bc$$2rdamedia
000933083 338__ $$aonline resource$$bcr$$2rdacarrier
000933083 4901_ $$aProgress in Inflammation Research Ser. ;$$vv.85
000933083 506__ $$aAccess limited to authorized users.
000933083 520__ $$aNrf2, a transcription factor that mediates transcriptional responses to oxidative and xenobiotic stresses, plays a central role in cellular protection against internal or external toxins. Defects in Nrf2 and the relevant regulatory pathways are associated with a number of pathologies including inflammation,respiratory diseases, cardiovascular dysfunctions, metabolic syndrome and diabetes, neurodegeneration, and cancer. This book comprehensively reviews the up-to-date discoveries for the roles of Nrf2 in several human diseases in the context of inflammation. In particular, the molecular mechanisms that mediate the functions of Nrf2 and its interacting network in inflammation and pathogenesis are explicated. In addition, the research and therapeutic applications of Nrf2-targeting compounds in different diseases were summarized. This book is expected to be a valuable reference for worldwide researchers conducting both mechanistic and therapeutic studies of Nrf2 and relevant factors.
000933083 588__ $$aDescription based on print version record.
000933083 650_0 $$aTranscription factors.
000933083 7001_ $$aDeng, Huai.
000933083 77608 $$iPrint version:$$aDeng, Huai$$tNrf2 and Its Modulation in Inflammation$$dCham : Springer,c2020$$z9783030445973
000933083 830_0 $$aPIR (Series) ;$$vv. 85.
000933083 852__ $$bebk
000933083 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-44599-7$$zOnline Access$$91397441.1
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000933083 980__ $$aEBOOK
000933083 980__ $$aBIB
000933083 982__ $$aEbook
000933083 983__ $$aOnline
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