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000933272 019__ $$a1155323146$$a1155874043$$a1156774608$$a1157415965$$a1158365191
000933272 020__ $$a9783030422462$$q(electronic book)
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000933272 0247_ $$a10.1007/978-3-030-42246-2$$2doi
000933272 0248_ $$a10.1007/978-3-030-42
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000933272 24500 $$aMolecular genetics of axial patterning, growth and disease in drosophila eye /$$cAmit Singh, Madhuri Kango-Singh, editors.
000933272 250__ $$a2nd ed.
000933272 264_1 $$aCham :$$bSpringer,$$c2020.
000933272 300__ $$a1 online resource (xiv, 368 pages) :$$billustrations.
000933272 336__ $$atext$$btxt$$2rdacontent
000933272 337__ $$acomputer$$bc$$2rdamedia
000933272 338__ $$aonline resource$$bcr$$2rdacarrier
000933272 347__ $$atext file$$bPDF$$2rda
000933272 5050_ $$aEarly eye development: Specification and Determination -- Generation of third dimension: Axial patterning in the developing Drosophila eye -- Catching the Next Wave: Patterning of the Drosophila eye by the Morphogenetic Furrow -- Ghost in the Machine- the Peripodail Epithelium -- Cell Polarity in Drosophila Retina -- Negative regulation for neural patterning in the Drosophila eye -- Adhesion and the cytoskeleton in the Drosophila pupaleye -- Drosophila eye as a model to study regulation of growth control: The discovery of size control pathways -- Drosophila cancer modeling using the eye imaginal discs -- Recent contributions of the Drosophila eye to unraveling the basis of neurodegeneration -- Genetic regulation of early eye development in non-dipteran insects -- Eyes for an eye: A comparative account on compound eye of Drosophila melanogaster with vertebrate eye -- Index.
000933272 506__ $$aAccess limited to authorized users.
000933272 520__ $$aDrosophila melanogaster (fruit fly) is a highly versatile model with a genetic legacy of more than a century. It provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases. One of the most important questions in biology is how a multi-cellular organism develops from a single-celled embryo. The discovery of the genes responsible for pattern formation has helped refine this question and has led to other questions, such as the role of various genetic and cell biological pathways in regulating the process of pattern formation and growth during organogenesis. The Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa. This updated second edition covers current progress in the study of molecular genetic mechanisms of pattern formation, mutations in axial patterning, genetic regulation of growth, and more using the Drosophila eye as a model.
000933272 650_0 $$aDrosophila$$xDevelopment.
000933272 650_0 $$aDrosophila$$xPhysiology.
000933272 650_0 $$aDrosophila$$xGenetics.
000933272 650_0 $$aHuman genetics.
000933272 650_0 $$aAnimal models in research.
000933272 650_0 $$aAnimal genetics.
000933272 7001_ $$aSingh, Amit,$$cPhD,$$eeditor.
000933272 7001_ $$aKango-Singh, Madhuri,$$eeditor.
000933272 77608 $$iPrint version:$$z9783030422455
000933272 852__ $$bebk
000933272 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-42246-2$$zOnline Access$$91397441.1
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