Myosins : A Superfamily of Molecular Motors / edited by Lynne M. Coluccio.
Coluccio, Lynne M., editor.
2020
QH506 .M96 2020
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Title
Myosins : A Superfamily of Molecular Motors / edited by Lynne M. Coluccio.
Edition
2nd ed. 2020.
ISBN
9783030380625
3030380629
9783030380618
DOI
https://doi.org/10.1007/978-3-030-38062-5
Published
Cham : Springer International Publishing : Imprint: Springer, 2020.
Language
English
Description
1 online resource (xi, 455 pages) : illustrations.
Item Number
10.1007/978-3-030-38062-5 doi
Call Number
QH506 .M96 2020
Dewey Decimal Classification
611.01816
Summary
Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. Myosins are involved in multiple cellular activities including cell structure, cell migration, intracellular trafficking, and cell-cell contact. Importantly, loss of function and mutation are associated with diseases including myopathies, hearing impairment, glomerulosclerosis, and cancer. Written by international experts in myosin motors and the approaches used to study them, this book is expected to provide a comprehensive assessment of the current status of our understanding of the structure and molecular mechanism of myosins and their cellular roles.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Added Author
Coluccio, Lynne M., editor.
Series
Advances in experimental medicine and biology ; 1239.
Available in Other Form
Print version: 9783030380618
Linked Resources
Online Access
Record Appears in
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Introduction
Myosin Structure
Cargo Binding by Unconventional Myosins
Cryo-EM of Actin-Myosin Structures
Small Molecule Effectors of Myosin Function
Single-Molecule Biophysical Techniques to Study Actomyosin Force Transduction
High-Speed Atomic Force Microscopy to Study Myosin Motility
How Myosin 5 Walks Deduced from Single-Molecule Biophysical Approaches
How Actin Tracks Affect Myosin Motors
Myosins in the Nucleus
Myosins in Cytokinesis
Myosins and Disease
Myosins and Hearing
The Actomyosin Systems in Apicomplexa
Approaches to Identify and Characterise MYO6-Cargo Interactions
Class IX Myosins: Motorized RhoGAP Signaling Molecules
Myosin X
Myosin XVI
Myosin XVIII
Myosin XIX.

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