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000937196 019__ $$a1162226918$$a1163823259$$a1164667449
000937196 020__ $$a9789811547980$$q(electronic book)
000937196 020__ $$a981154798X$$q(electronic book)
000937196 020__ $$z9789811547973
000937196 0247_ $$a10.1007/978-981-15-4
000937196 035__ $$aSP(OCoLC)on1157078985
000937196 035__ $$aSP(OCoLC)1157078985$$z(OCoLC)1162226918$$z(OCoLC)1163823259$$z(OCoLC)1164667449
000937196 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dLQU$$dOCLCF
000937196 049__ $$aISEA
000937196 050_4 $$aRC388.5
000937196 08204 $$a616.8/1042$$223
000937196 24500 $$aIschemiRs :$$bmicroRNAs in ischemic stroke : from basics to clinics /$$cRajanikant G. K., Pierre Gressens, Sreekala S. Nampoothiri, Gokul Surendran, Cindy Bokobza.
000937196 260__ $$aSingapore :$$bSpringer,$$c2020.
000937196 300__ $$a1 online resource (146 pages)
000937196 336__ $$atext$$btxt$$2rdacontent
000937196 337__ $$acomputer$$bc$$2rdamedia
000937196 338__ $$aonline resource$$bcr$$2rdacarrier
000937196 504__ $$aIncludes bibliographical references.
000937196 5050_ $$aPreface -- Chapter 1: microRNAs in normal brain physiology -- Chapter 2: Ischemic stroke: An imperative need for effective therapy -- Chapter 3: MicroRNAs in ischemic stroke pathophysiology: Special emphasis on early molecular events -- Chapter 4: microRNA regulation of ischemic stroke inflammatory and immune response -- Chapter 5: Regulatory role of microRNAs in ischemic cell death -- Chapter 6: The emerging role of microRNAs in post-ischemic angiogenesis and neurogenesis -- Chapter 7: MicroRNAs as potential diagnostic, prognostic and therapeutic biomarkers in ischemic stroke -- Chapter 8: Interplay between microRNAs and other cerebrovascular diseases -- Chapter 9: New insights into the regulatory role of lncRNA, circRNA, piRNAs, and ceRNAs in ischemic stroke -- Chapter 10: Computational resources for microRNA research -- Chapter 11: MicroRNA-targeted therapeutics for ischemic stroke: Status, gaps and the way forward.
000937196 506__ $$aAccess limited to authorized users.
000937196 520__ $$aThere has been an enormous increase in information relating to microRNA (miRNA) and its strategic role in numerous diseases. This book reviews the emerging role of microRNAs in cerebral ischemia, providing comprehensive details of the links between this small RNA molecule and ischemic stroke, the more prevalent of the two main types of stroke. The chapters address questions relating to microRNAs function in various pathological features of stroke, like oxidative stress, excitotoxicity and cell death, as well as its role as a biomarker and diagnostic agent, and the current therapeutic interventions. Further, the book highlights the latest research on how miRNAs contribute to neuroregeneration following stroke, discussing the myriad computational tools and databases used in miRNA research, and decsribes how how miRNA modulates other cerebrovascular diseases. The book concludes with fresh insights into the effect of long non-coding RNA in cerebral ischemia.
000937196 588__ $$aDescription based on print version record.
000937196 650_0 $$aCerebral ischemia$$xGenetic aspects.
000937196 650_0 $$aMicroRNA.
000937196 7001_ $$aG. K., Rajanikant.
000937196 7001_ $$aGressens, Pierre.
000937196 7001_ $$aNampoothiri, Sreekala S.
000937196 7001_ $$aSurendran, Gokul.
000937196 7001_ $$aBokobza, Cindy.
000937196 77608 $$iPrint version:$$aG. K., Rajanikant$$tIschemiRs: MicroRNAs in Ischemic Stroke$$dSingapore : Springer Singapore Pte. Limited,c2020$$z9789811547973
000937196 852__ $$bebk
000937196 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-15-4798-0$$zOnline Access$$91397441.1
000937196 909CO $$ooai:library.usi.edu:937196$$pGLOBAL_SET
000937196 980__ $$aEBOOK
000937196 980__ $$aBIB
000937196 982__ $$aEbook
000937196 983__ $$aOnline
000937196 994__ $$a92$$bISE