000938322 000__ 02830cam\a2200433Ia\4500 000938322 001__ 938322 000938322 005__ 20230306151801.0 000938322 006__ m\\\\\o\\d\\\\\\\\ 000938322 007__ cr\un\nnnunnun 000938322 008__ 200716s2020\\\\si\\\\\\o\\\\\000\0\eng\d 000938322 019__ $$a1178999056$$a1182455726$$a1182917528$$a1183931145 000938322 020__ $$a9789811555305$$q(electronic book) 000938322 020__ $$a9811555303$$q(electronic book) 000938322 020__ $$z981155529X 000938322 020__ $$z9789811555299 000938322 0247_ $$a10.1007/978-981-15-5 000938322 035__ $$aSP(OCoLC)on1164826829 000938322 035__ $$aSP(OCoLC)1164826829$$z(OCoLC)1178999056$$z(OCoLC)1182455726$$z(OCoLC)1182917528$$z(OCoLC)1183931145 000938322 040__ $$aYDX$$beng$$cYDX$$dGW5XE$$dEBLCP$$dLQU 000938322 049__ $$aISEA 000938322 050_4 $$aQP551 000938322 08204 $$a572/.6$$223 000938322 24500 $$aFrontiers in protein structure, function, and dynamics /$$cDev Bukhsh Singh, Timir Tripathi, editors. 000938322 260__ $$aSingapore :$$bSpringer,$$c2020. 000938322 300__ $$a1 online resource 000938322 336__ $$atext$$btxt$$2rdacontent 000938322 337__ $$acomputer$$bc$$2rdamedia 000938322 338__ $$aonline resource$$bcr$$2rdacarrier 000938322 506__ $$aAccess limited to authorized users. 000938322 520__ $$aThis book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecular motors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction. 000938322 650_0 $$aProteins. 000938322 650_0 $$aProteins$$xStructure. 000938322 7001_ $$aSingh, Dev Bukhsh. 000938322 7001_ $$aTripathi, Timir. 000938322 77608 $$iPrint version: $$z981155529X$$z9789811555299$$w(OCoLC)1152479333 000938322 852__ $$bebk 000938322 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-15-5530-5$$zOnline Access$$91397441.1 000938322 909CO $$ooai:library.usi.edu:938322$$pGLOBAL_SET 000938322 980__ $$aEBOOK 000938322 980__ $$aBIB 000938322 982__ $$aEbook 000938322 983__ $$aOnline 000938322 994__ $$a92$$bISE