000944878 000__ 03790cam\a2200433M\\4500 000944878 001__ 944878 000944878 005__ 20230306152313.0 000944878 006__ m\\\\\o\\d\\\\\\\\ 000944878 007__ cr\un\nnnunnun 000944878 008__ 201008s2020\\\\xx\\\\\\o\\\\\0||\0\eng\d 000944878 019__ $$a1202464263$$a1203986274$$a1204301010$$a1206408922 000944878 020__ $$a9789811559174$$q(electronic book) 000944878 020__ $$a9811559171$$q(electronic book) 000944878 020__ $$z9811559163 000944878 020__ $$z9789811559167 000944878 0247_ $$a10.1007/978-981-15-5917-4$$2doi 000944878 035__ $$aSP(OCoLC)on1199127625 000944878 035__ $$aSP(OCoLC)1199127625$$z(OCoLC)1202464263$$z(OCoLC)1203986274$$z(OCoLC)1204301010$$z(OCoLC)1206408922 000944878 040__ $$aYDX$$beng$$cYDX$$dEBLCP$$dDCT$$dSFB$$dN$T 000944878 049__ $$aISEA 000944878 050_4 $$aRS380 000944878 08204 $$a615.19$$223 000944878 24500 $$aBotanical Leads for Drug Discovery. 000944878 260__ $$a[S.l.] :$$bSPRINGER VERLAG, SINGAPOR,$$c2020. 000944878 300__ $$a1 online resource 000944878 336__ $$atext$$btxt$$2rdacontent 000944878 337__ $$acomputer$$bc$$2rdamedia 000944878 338__ $$aonline resource$$bcr$$2rdacarrier 000944878 347__ $$atext file$$bPDF$$2rda 000944878 506__ $$aAccess limited to authorized users. 000944878 520__ $$aActive botanical ingredients are a prime requirement for herbal formulations and discovering a drug is all about integration of science disciplines. In recent decades there has been a growing interest in treating wounds and diseases using traditional remedies based on local herbs, combined with chemical advances. Although this has led to the development of new bioactive ingredients from plants, there has been little success in terms of clinical trials and post-marketing studies to comply with FDA guidelines. Plants have been used as a source of medicine throughout history and continue to serve as the basis for many pharmaceuticals used today. However, despite the modern pharmaceutical industry being founded on botanical medicine, synthetic approaches to drug discovery have now become standard. Science-driven translational discovery and botanical development has created a new reality, leading to enormous changes in strategies, technologies and the disciplines involved, which have been embraced by the pharmaceutical and biotech industries. This book gathers scientific expertise and traditional knowledge to promote the discovery and development of new formulations and drugs based on active ingredients and to provide guidance on taking these to clinical trials. It discusses major topics, such as how the phytochemical composition of many plants has changed over time due to factors like cultivation, which can have both positive and negative effects on the levels of bioactive compounds. It also explores the importance of plants as a valuable source of therapeutic compounds as a result of their vast biosynthetic capacity, and classifies them according to their intended use, safety and regulatory status. Further, the book offers insights into the regulatory aspects of botanical products, which is an important issue when considering standardization and quality assessment, and also examines the commercial aspects of plant-derived medications and their proven role in the treatment of chronic diseases such as heart disease, high blood pressure, pain, asthma, and other associated conditions. Given its scope, this book is a valuable tool for botanists, natural product chemists, pharmacologists and microbiologists involved in the study of phytochemicals for drug discovery. 000944878 650_0 $$aPharmaceutical technology. 000944878 650_0 $$aDrug resistance. 000944878 7001_ $$aSingh, Bikarma,$$eeditor. 000944878 77608 $$iPrint version: $$z9811559163$$z9789811559167$$w(OCoLC)1153310546 000944878 852__ $$bebk 000944878 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-15-5917-4$$zOnline Access$$91397441.1 000944878 909CO $$ooai:library.usi.edu:944878$$pGLOBAL_SET 000944878 980__ $$aEBOOK 000944878 980__ $$aBIB 000944878 982__ $$aEbook 000944878 983__ $$aOnline 000944878 994__ $$a92$$bISE