000945118 000__ 04827cam\a2200541Mi\4500 000945118 001__ 945118 000945118 005__ 20230306152501.0 000945118 006__ m\\\\\o\\d\\\\\\\\ 000945118 007__ cr\nn\nnnunnun 000945118 008__ 201003s2020\\\\gw\\\\\\o\\\\\|||\0\eng\d 000945118 019__ $$a1199056003$$a1202450550$$a1202481259$$a1206399457$$a1223089450 000945118 020__ $$a9783030478018 000945118 020__ $$a3030478017 000945118 020__ $$z9783030478018 000945118 020__ $$z3030478009 000945118 020__ $$z9783030478001 000945118 0247_ $$a10.1007/978-3-030-47801-8.$$2doi 000945118 035__ $$aSP(OCoLC)on1203209748 000945118 035__ $$aSP(OCoLC)1203209748$$z(OCoLC)1199056003$$z(OCoLC)1202450550$$z(OCoLC)1202481259$$z(OCoLC)1206399457$$z(OCoLC)1223089450 000945118 040__ $$aEQF$$beng$$cEQF$$dEBLCP$$dERF$$dOCLCO$$dYDX 000945118 049__ $$aISEA 000945118 050_4 $$aRC681-688.2 000945118 08204 $$a616.12$$223 000945118 24500 $$aMicrocirculation in Cardiovascular Diseases /$$cedited by Enrico Agabiti-Rosei, Anthony M. Heagerty, Damiano Rizzoni. 000945118 250__ $$a1st ed. 2020. 000945118 264_1 $$aCham :$$bSpringer International Publishing :$$bImprint: Springer,$$c2020. 000945118 300__ $$a1 online resource (viii, 216 pages) :$$billustrations. 000945118 336__ $$atext$$btxt$$2rdacontent 000945118 337__ $$acomputer$$bc$$2rdamedia 000945118 338__ $$aonline resource$$bcr$$2rdacarrier 000945118 4901_ $$aUpdates in Hypertension and Cardiovascular Protection,$$x2366-4606 000945118 5050_ $$aChapter 1 Structure and Function of the Microcirculation -- Chapter 2 Assessment of Small Artery Structure and Function by Micromyography -- Chapter 3 Assessment of Retinal Arteriolar Morphology by SLDF -- Chapter 4 Assessment of Retinal Arteriolar Morphology by Adaptive Optics -- Chapter 5 The Cerebral Microcirculation -- Chapter 6 Role of Inflammation in Microvascular Damage -- Chapter 7 Immune Mechanisms in Vascular Remodeling in Hypertension -- Chapter 8 Microvascular Endothelial Dysfunction in Hypertension -- Chapter 9 Interrelationships Between Micro and Macrocirculation -- Chapter 10 Alterations in Capillary and Microcirculatory Networks in Cardiovascular Diseases -- Chapter 11 Microvascular Alterations in Obesity -- Chapter 12 Microvascular Alterations in Diabetes: Focus on Small Resistance Arteries -- Chapter 13 Cardiovascular Effects of Anti-angiogenic Drugs -- Chapter 14 Pathophysiological Mechanisms Implicated in Organ Damage and Cardiovascular Events -- Chapter 15 The Role of Perivascular Adipose Tissue in Arterial Function in Health and Disease -- Chapter 16 Prognostic Role of Microvascular Damage and Effect of Treatment. 000945118 506__ $$aAccess limited to authorized users. 000945118 520__ $$aThis book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers. 000945118 650_0 $$aCardiology. 000945118 650_0 $$aCardiovascular system. 000945118 650_0 $$aGeriatric nursing. 000945118 650_0 $$aOphthalmology. 000945118 650_0 $$aChemotherapy. 000945118 7001_ $$aAgabiti Rosei, Enrico,$$eeditor. 000945118 7001_ $$aHeagerty, Anthony M.,$$eeditor. 000945118 7001_ $$aRizzoni, Damiano.,$$eeditor. 000945118 77608 $$iPrint version:$$aAgabiti-Rosei, Enrico$$tMicrocirculation in Cardiovascular Diseases$$dCham : Springer International Publishing AG,c2020$$z9783030478001 000945118 830_0 $$aUpdates in hypertension and cardiovascular protection,$$x2366-4606 000945118 852__ $$bebk 000945118 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-47801-8$$zOnline Access$$91397441.1 000945118 909CO $$ooai:library.usi.edu:945118$$pGLOBAL_SET 000945118 980__ $$aEBOOK 000945118 980__ $$aBIB 000945118 982__ $$aEbook 000945118 983__ $$aOnline 000945118 994__ $$a92$$bISE