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000945420 019__ $$a1200494550
000945420 020__ $$a3030412075
000945420 020__ $$a9783030412074
000945420 020__ $$z3030412067
000945420 020__ $$z9783030412067
000945420 0247_ $$a10.1007/978-3-030-41207-4$$2doi
000945420 035__ $$aSP(OCoLC)on1204152440
000945420 035__ $$aSP(OCoLC)1204152440$$z(OCoLC)1200494550
000945420 040__ $$aSFB$$beng$$cSFB$$dOCLCO$$dYDX
000945420 049__ $$aISEA
000945420 050_4 $$aR895-920
000945420 08204 $$a616.0757$$223
000945420 24500 $$aBreast MRI for High-risk Screening /$$cedited by Francesco Sardanelli, Franca Podo.
000945420 250__ $$a1st ed. 2020.
000945420 264_1 $$aCham :$$bSpringer International Publishing :$$bImprint: Springer,$$c2020.
000945420 300__ $$a1 online resource (XXIII, 376 pages) :$$billustrations.
000945420 336__ $$atext$$btxt$$2rdacontent
000945420 337__ $$acomputer$$bc$$2rdamedia
000945420 338__ $$aonline resource$$bcr$$2rdacarrier
000945420 5050_ $$aIntroduction -- Thirty years of contrast enhanced breast MRI -- The mantra about low specificity breast MRI -- BRCA and other genes conferring hereditary breast cancer predisposition -- Screening mammography: One size fits all? -- MRI protocols for breast cancer screening -- Contrast materials for screening MRI and concerns about tissue deposition -- Applying MRI BI-RADS in a high-risk population -- CAD systems for breast MRI screening -- Phenotype presentation and radiogenomics of breast cancer with special focus on high-risk women -- The body of primary evidence about MRI for high risk screening: retrospective and prospective studies -- High-risk screening: MRI alone? -- Secondary evidence from systematic reviews and meta-analyses -- Radioprotection issues for women with hereditary predisposition for breast cancer -- Impact of MRI screening on high-risk patient outcome -- The special case of previous chest radiation therapy -- IT infrastructure for data managing in multicenter high-risk screening -- Guidelines and recommendations all over the world: agreements and differences -- Medical options: Pharmacopreventio- Surgical options: Prophylactic mastectomy and oophorectomy -- Psychosocial aspects of high-risk of breast cancer -- Calculating, using and improving individual breast cancer risk estimates -- MRI for screening women with a personal history of breast cancer -- Screening MRI for the intermediate risk: an open issue -- Looking at the future: Personalized breast cancer screening -- Acknowledgments. 
000945420 506__ $$aAccess limited to authorized users.
000945420 520__ $$aThis book offers a comprehensive overview of the use of breast MRI for screening high-risk women, including those with familial-genetic hereditary predisposition and previous chest radiation therapy, typically lymphoma survivors. It discusses the historical background of studies and research that provided the body of evidence in favor of MRI screening of these women. Technical and clinical topics are treated in dedicated chapters, including models for individualized risk estimation, radiogenomics of breast cancer in high-risk women, computer-aided detection/diagnosis and machine learning systems applied to breast MRI, and psycho-oncology issues. Alternatives to breast MRI screening such as pharmaco-prevention and prophylactic mastectomy are also discussed, taking into account the public debate on the "Angelina Jolie" effect. The high breast cancer risk model is proposed as a paradigm for personalized medicine. This book will be of interest to radiologists, surgeons, oncologists and to all professionals devoted to female healthcare.
000945420 650_0 $$aRadiology.
000945420 650_0 $$aOncology.
000945420 650_0 $$aSurgery.
000945420 650_0 $$aEpidemiology.
000945420 650_0 $$aHuman genetics.
000945420 7001_ $$aSardanelli, Francesco.$$eeditor.
000945420 7001_ $$aPodo, Franca.$$eeditor.
000945420 852__ $$bebk
000945420 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-41207-4$$zOnline Access$$91397441.1
000945420 909CO $$ooai:library.usi.edu:945420$$pGLOBAL_SET
000945420 980__ $$aEBOOK
000945420 980__ $$aBIB
000945420 982__ $$aEbook
000945420 983__ $$aOnline
000945420 994__ $$a92$$bISE